动脉自旋标记技术在儿童中枢神经系统检查中的应用

Application of Arterial Spin Labeling Technique in Children Central Nervous System Examination

动脉自旋标记技术(ASL)是将脉冲标记的动脉血中水的氢质子作为内源性对比剂研究大脑灌注情况的一种功能磁共振技术,有效避免了外源性对比剂带来的潜在风险,使其以无创、可重复检查等优点更适用于临床检查,尤其是婴幼儿及儿童的检查。目前中枢神经系统疾病是临床关注的高发疾病之一,而ASL对颅脑疾病的检查及诊断具有一定的价值,不仅可以用于脑部疾病不同阶段血流灌注情况的评估,还可以对局部区域脑血流量与该区域神经活动的关系进行监测。

Arterial spin labeling（ASL） is a functional magnetic resonance imaging technique that uses pulsed-labeled hydrogen protons of water in arterial blood as an endogenous contrast agent to study cerebral perfusion,effectively avoiding the potential risks from the exogenous contrast medium.With the advantages of noninvasiveness and repeatable inspection,it is more suitable for clinical examination,especially in infants and children.Diseases of the central nervous system is currently one of the diseases with high incidence in clinical,and ASL also has a certain value for inspection and diagnosis of cerebral diseases,which can be used not only to assess brain disease condition of different stages of blood perfusion,but also to monitor the relationship between the local cerebral blood flow and neural activity.