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Residual urinary output in high body mass index individuals on chronic hemodialysis:A disregarded life vest? 被引量:1

Residual urinary output in high body mass index individuals on chronic hemodialysis:A disregarded life vest?
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摘要 AIM: To assess residual diuresis and diverse variables according to body mass index (BMI).METHODS: Cross-sectional study (n = 57), with 3 groups. Group A: BMI 〈 25, n = 22; Group B: BMI 25-30, n = 15; Group C: BMI 〉 30, n = 20. Diuresis, hematocrit, albumin, C-reactive protein, Malnutrition infammatory score, Pro-BNP, Troponin T, leptin and in-sulin levels are expressed as median and ranges (r). RESULTS: Albumin (g/dL): GA vs GC, 3.70 (r2.20-4.90) vs 3.85 (r3.40-4.90), P = 0.02. Diuresis (mL/d): GA 690 (r0-1780); GB 660 (r60-1800); GC 840 (r40-2840). Diuresis GA vs GC, P = 0.01. Leptin (ng/mL): GA vs GC, 3.81 (r0.78-69.60) vs GC, 32.80 (r0.78-124.50), P 〈 0.001. Insulin (μU/mL): GA vs GB, 7 (r2-44) vs 11.50 (r4-38), P = 0.02; GA vs GC, 7 (r2-44) vs 19.5 (r5-155), P = 0.0001. Troponin T and Pro-BNP levels were not different. Significant correlations: GC, Insulin-UF: ρ= 0.53; P = 0.03; TroponinT-diuresis: ρ = -0.48, P 〈 0.05; Pro-BNP-diuresis: ρ = -0.39, P 〈 0.01; Troponin T-ProBNP: ρ = 0.77, P 〈 0.0001; albumin-Troponin T: ρ = -0.66, P 〈 0.0001; albumin-ProBNP: ρ = -0.44, P 〈 0.05.CONCLUSION: High BMI associated positively with higher diuresis and albuminemia, and negatively with TropT and Pro-BNP. High BMI-associated better survival may be explained by better urinary output, lowering cardiovascular stress. AIM:To assess residual diuresis and diverse variables according to body mass index(BMI).METHODS:Cross-sectional study(n = 57),with 3groups.Group A:BMI < 25,n = 22; Group B:BMI25-30,n = 15; Group C:BMI > 30,n = 20.Diuresis,hematocrit,albumin,C-reactive protein,Malnutrition inflammatory score,Pro-BNP,Troponin T,leptin and insulin levels are expressed as median and ranges(r).RESULTS:Albumin(g/dL):GA vs GC,3.70(r2.20-4.90)vs 3.85(r3.40-4.90),P = 0.02.Diuresis(m L/d):GA690(r0-1780); GB 660(r60-1800); GC 840(r40-2840).Diuresis GA vs GC,P = 0.01.Leptin(ng/m L):GA vs GC,3.81(r0.78-69.60) vs GC,32.80(r0.78-124.50),P< 0.001.Insulin(μU/mL):GA vs GB,7(r2-44) vs 11.50(r4-38),P = 0.02; GA vs GC,7(r2-44) vs 19.5(r5-155),P = 0.0001.Troponin T and Pro-BNP levels were not different.Significant correlations:GC,Insulin-UF:ρ= 0.53; P = 0.03; Troponin T-diuresis:ρ =-0.48,P < 0.05; Pro-BNP-diuresis:ρ =-0.39,P < 0.01; Troponin T-ProB NP:ρ = 0.77,P < 0.0001; albumin-Troponin T:ρ =-0.66,P < 0.0001; albumin-ProB NP:ρ =-0.44,P < 0.05.CONCLUSION:High BMI associated positively with higher diuresis and albuminemia,and negatively with TropT and Pro-BNP.High BMI-associated better survival may be explained by better urinary output,lowering cardiovascular stress.
出处 《World Journal of Nephrology》 2014年第4期317-323,共7页 世界肾病学杂志(英文版)
关键词 HEMODIALYSIS Residual diuresis Body mass index Troponin T PRO-BNP Insulin 体质指数 红细胞压积 肾病 治疗方法
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