铈掺量对羟基磷灰石结构及吸附性能的影响

Effect of cerium content on hydroxyapatite structure and adsorption property

羟基磷灰石(HAp)由于其良好的生物相容性和生物活性,而在生物医学方面具有广泛的应用.为了寻找更好的生物载体材料,采用湿化学沉淀法制备出了不同剂量(0mol%、2mol%、4mol%、6 mol%、8 mol%、10 mol%)铈掺杂的羟基磷灰石材料(CeHAp),并通过XRD、FTIR、HRTEM、XPS等对样品进行结构和化学分析.同时,还研究了CeHAp对牛血清蛋白(BSA)的吸附性能.研究结果表明,随着铈掺量的增加,样品的结晶度降低、晶粒尺寸减小;当Ce^(3+)和Ce^(4+)被掺入HAp中时,BSA吸附性随着铈掺量的增加而增加.

Hydroxyapatite is widely used in biomedicine because of its good biocompatibility and biological activity. In order to find better biomaterials, different doping amounts （0 mol%,2 mol%,4 mol%,6 mol%,8 mol%,10 mol%） of cerium （Ce） were doped into HAp by wet chemical method. The structure and chemical analysis of the samples were character ized by XRD,FTIR, HRTEM,XPS and so on. Moreover, the bovine serum albumin （BSA） adsorption of the samples was evaluated. The results indicated that the crystallinity and crys tallite size of the samples decreased with the increase doping amount of cerium. Ce3＋ and Ce4＋ have been incorporated into the HAp lattice,and the BSA adsorption properties of Ce HAp particles were found to increase with increasing cerium content.