用颈交感干和舌下神经袢再支配狗环杓后肌的研究

Reinnervation of the Canine Posterior Cricoarytenoid Muscles With Sympathetic Preganglionic Neurons and Ansa Hypoglossi

将８只狗的右侧喉返神经及其内收支切断，再分别将其中４只狗的右侧颈交感神经干和２只狗的右侧舌下神经袢切断后，各将其近侧端和已切断的喉返神经的远侧端吻合，其余２只狗作为失神经支配的对照组。分别于术前、术后即刻及术后４个月行声门照像、肌电图观察，最后行环杓后肌肉眼及组织化学观察。实验结果证明：采用两种神经修复喉返神经均可部份恢复环杓后肌功能，论证了用颈交感神经干修复的机理及各种神经修复法的优缺点，为今后进一步的研究和临床应用提供理论依据。

The right recurrent laryngeal nerves were sectioned in eight dogs.With the right sympathetic cervical trunks in 4 and the right ansa hypoglossi in 2 cut off and then sutured with the sectioned caudal end of the recurrent laryngeal nerves. The remaining two served as denervated controls without neurorrhaphy as the above-mentioned.All of them underwent photolaryngoscopy and electromyography in the following interval:preoperative,immediately after postoperation,and four months later.Then the PCA muscles were observed,with naked eves and examined by the method of histochemistry.These results of our experiment proved that:Both the two reinnervational methods could partially resume the function of PCA muscles.The mechanism of reinnervation with sympathetic cervical trunks and the comparison of several repaired methods were discussed.It will provide the theoretical basis for further study and clinical application in future.