肺宁颗粒治疗小儿支气管炎并发热、咳喘的疗效研究

Efficacy research of Feining Granule in the treatment of infantile bronchitis with fever, cough and dyspnea

目的探讨肺宁颗粒治疗小儿支气管炎并发热、咳喘的临床疗效。方法 80例小儿支气管炎并发热、咳喘患儿,采用随机数字表法分为对照组和观察组,各40例。对照组在常规基础上给予利巴韦林颗粒、阿奇霉素干混悬剂治疗,观察组在对照组基础上给予肺宁颗粒治疗。比较两组患儿治疗效果及治疗后退热时间、咳喘消失时间、肺部啰音消失时间、不良反应发生情况。结果观察组患儿治疗后退热时间、咳喘消失时间以及肺部啰音消失时间均明显短于对照组,差异具有统计学意义(P<0.05)。对照组患儿总有效率为77.50%(31/40),观察组患儿总有效率为95.00%(38/40),观察组总有效率明显高于对照组,差异具有统计学意义(P<0.05)。两组患儿治疗期间均未出现明显不良反应。结论肺宁颗粒可显著缩短小儿支气管炎患儿发热、咳喘以及肺部啰音等症状消退时间,临床疗效确切,且用药安全,值得推广应用。

Objective To investigate the clinical efficacy of Feining Granule in the treatment of infantile bronchitis with fever, cough and dyspnea. Methods A total of 80 cases of infantile bronchitis with fever, cough and dyspnea were divided into control group and observation group according to the random number table method, 40 cases in each group. The control group was given Ribavirin Granules and Azithromycin for Suspension on the basis of conventional treatment, the observation group was given Feining Granules on the basis of the control group. The therapeutic effect, antipyretic time, disappearance time of cough and dyspnea, disappearance time of pulmonary rales and the occurrence of adverse reactions after treatment between the two groups were compared. Results The antipyretic time, disappearance time of cough and dyspnea, disappearance time of pulmonary rales in the observation group after treatment were significantly shorter than those in the control group, the differences were statistically significant（P〈0.05）. The total effective rate of the control group was 77.50%（31/40） and that of the observation group was 95.00%（38/40）. The total effective rate of the observation group was significantly higher than that in the control group, the difference was statistically significant（P〈0.05）. No obvious adverse reactions were observed in the two groups during treatment. Conclusion Feining Granule can significantly shorten the remission time of fever, cough and dyspnea, pulmonary rales in infantile bronchitis. It has a definite clinical effect, is safe to use and worthy of popularization and application.