探讨脑钠肽在急性肺栓塞危险分层中的价值

Exploring Value of Brain Natriuretic Peptide in Risk Stratification of Acute Pulmonary Embolism

目的探讨血清脑钠肽(BNP)对急性肺血栓栓塞症(APTE)危险分层的临床价值。方法选择承德医学院附属医院呼吸内科2013年1月至2016年7月确诊APTE并行外周血BNP检查的84例患者,按照BNP水平,分为BNP升高组41例与BNP正常组43例。比较两组患者临床特点、右心功能障碍、中央型肺栓塞、低危及中危APTE发生率及住院期间死亡率。结果两组低氧血症、右室扩大、肺动脉高压、中央型肺栓塞、低危组和中危组APTE发生率经统计学处理差异有统计学意义。BNP升高组死亡1例。BNP正常组无死亡患者。结论 BNP可作为APTE患者危险分层的指标,有利于指导治疗。

Objective to explore clinical value of serum brain natriuretic peptide（BNP） in risk stratification of acute pulmonary thromboembolism（APTE）. Methods choose 84 cases APTE patients with peripheral blood BNP examination from January 2013 to July 2016 in respiratory department of Chengde Medical College Affiliated Hospital. According to BNP level, divide them into BNP increasing group 41 cases and normal BNP group 43 cases. Compare clinical characteristics, right heart dysfunction, central pulmonary embolism, incidence of low and medium risk APTE and mortality during hospitalization between two groups. Results with statistical treatment, difference of hypoxemia, right ventricular enlargement, pulmonary artery hypertension, central pulmonary embolism, low and medium risk group APTE incidence showed statistical significance between two groups. 1 case died in BNP increasing group, no death in normal BNP group. Conclusion BNP can be used as an indicator of risk stratification of APTE patients, which is conductive to guiding treatment.