经皮椎体成形术对老年骨质疏松性胸腰椎压缩性骨折患者骨密度、Cobb角的影响研究

Effect Study of Percutaneous Vertebroplasty on Bone Density and Cobb Angle of Elderly Patients with Osteoporotic Thoracolumbar Vertebral Compression Fractures

目的探讨经皮椎体成形术对老年骨质疏松性胸腰椎压缩性骨折患者骨密度、Cobb角的影响。方法选取我院2015年1月至2017年12月收治的老年骨质疏松性胸腰椎压缩性骨折患者122例,随机将研究对象分为观察组和对照组,每组各61例。对照组给予保守治疗,观察组给予经皮椎体成形术治疗。X线检查测定手术前和手术后3个月Cobb角、椎体前缘高度,应用视觉模拟评分(VAS)评估术前和术后3个月疼痛程度,使用骨密度仪检测治疗前后患者骨密度情况。结果治疗后两组骨密度和Cobb角均有明显改善(P<0.05),较对照组,观察组术后骨密度和Cobb角改善情况更加显著(P<0.05)。术后两组椎体前缘高度和VAS评分均明显改善,且观察组术后椎体前缘高度和VAS评分改善情况明显优于对照组(P<0.05)。结论经皮椎体成形术较保守治疗疗效显著,可有效改善患者骨密度,促进椎体愈合,缓解疼痛,值得进一步应用与推广。

Objective To investigate effect of percutaneous vertebroplasty on bone density and Cobb angle of elderly patients with osteoporotic thoraeolumbar vertebral compression fractures. Methods Chooae 122 cases osteoporotic thoracolumbar compression fracture patients treated in our hospital from January 2015 to December 2017, divide them into observation and control group randomly, 61 eases in each. Control group was treated with conservatiye treatment, and observation group with percutaneous vertebroplasty. Detect Cobb angle and anterior edge height of vertebral body with X - ray examination before and 3 months after opera.tion. With visual analogue scores （VAS）, evaluate pain level before and 3 months after operation, detect bone density with bone densitometer before and after operation. Results After treatment, bone density and Cobb angle of two groups was obviously improved （P〈0.05）. Compared with control group, improvement of bone density and Cobb angle of observation group was more significant （P〈0.05）. Postoperative anterior edge height of vertebral body and VAS scores of two groups were significantly improved, and improvement of anterior edge height of vertebral body and VAS scores of observation group was significantly better than control group （P〈0.05）. Conclusion percutaneous vertebroplasty has more significant effect than conservative treatment, which can improve bone density, promote healing of vertebral body and relieve pains effectively, and is worthy of further application and promotion.