早期胰岛素治疗妊娠期糖尿病患者效果观察

The Effect of Early Insulin Therapy on Gestational Diabetes Mellitus

目的探究早期胰岛素治疗对妊娠期糖尿病患者妊娠结局的影响效果。方法选取2017年1月—2018年6月我院收治的妊娠期糖尿病患者80例作为研究对象,将孕龄为24~28周的患者作为对照组(40例),孕龄在24周内的患者作为观察组(40例)。两组患者均使用胰岛素治疗,对比两组患者的妊娠结局、产后情况以及新生儿情况,进行统计学分析。结果观察组患者的死产率为5.00%,低于对照组患者(25.00%),但组间比较,差异不具有统计学意义(P> 0.05)。对比两组患者的产后情况,观察组患者的产后出血、高血压综合征、产后感染、其他并发症,均低于对照组患者,差异具有统计学意义(P <0.05)。观察组新生儿窒息、低体质量儿、巨大儿均低于对照组,差异具有统计学意义(P <0.05)。结论早期胰岛素治疗妊娠期糖尿病患者,减有助于减少新生儿死产率,降低孕产妇产后不良反应,改善妊娠结局。

Objective To explore the effect of early insulin therapy on pregnancy outcome in patients with gestational diabetes mellitus. Methods 80 cases of gestational diabetes mellitus admitted to our hospital from January 2017 to June 2018 were selected as the research objects. The patients with gestational age of 24-28 weeks were used as control group （40 cases）. The patients with gestational age within 24 weeks were selected as observation group （40 cases）. Two groups of patients were treated with insulin. The pregnancy outcome, postpartum condition and neonatal condition of the two groups were compared and analyzed statistically. Results The mortality rate of the observation group was 5.00%, lower than that of the control group （25.00%）, but there was no significant difference between the two groups （P 〉 0.05）. The postpartum hemorrhage, hypertension syndrome, postpartum infection and other complications in the observation group were lower than those in the control group （P 〈 0.05）. The neonatal asphyxia, low birth weight infants and macrosomia in the observation group were lower than those in the control group, and the difference was statistically signifcant （P 〈 0.05）. Conclusion Early insulin therapy for gestational diabetes mellitus can help reduce neonatal stillbirth rate, reduce maternal adverse reactions and improve pregnancy outcomes.