胸痹汤治疗不稳定型心绞痛气虚血瘀型患者30例

30 Cases of Unstable Angina Pectoris with Type of Qi Deficiency and Blood Stasis Treatment with Xiongbi Decoction

目的:观察胸痹汤治疗不稳定型心绞痛气虚血瘀型患者的临床疗效。方法:选取安徽中医药大学第一附属医院干部心内科2016年8月—2017年8月收治的气虚血瘀型冠心病不稳定型心绞痛患者60例,按照随机数字表将患者分为两组,各30例,对照组予以西医常规治疗,而观察组在对照组的基础上予以胸痹汤治疗,治疗过程分别为8周。观察比较对照组与观察组治疗前后临床效果、中医证候积分、心绞痛发作次数及时间、心电图、心功能。结果:两组患者的中医证候积分治疗后与治疗前比较明显下降(P <0. 05);两组患者中医证候积分治疗前与治疗后差值比较,差异具有统计学意义(P <0. 05);两组患者的临床效果对比,差异具有统计学意义(P <0. 05);两组患者心电图、心功能指标治疗后与治疗前比较明显好转,差异具有统计学意义(P <0. 05);两组患者的心绞痛发作次数及时间明显低于治疗前,差异具有统计学意义(P <0. 05);两组患者心功能指标、心绞痛发作次数及时间的治疗前与治疗后差值比较,差异具有统计学意义(P <0. 05)。结论:胸痹汤治疗气虚血瘀型冠心病不稳定型心绞痛效果显著,值得临床借鉴。

Objective ： To observe the clinical curative effect of Xiongbi Decoction in the treatment of Unstable Angina Pectoris with type of qi deficiency and blood stasis. Methods ：60 cases of unstable angina patients with type of qi deficiency and blood stasis from Cardiology Department of the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine in August 2016-2017 year in August were randomly divided into observation group and control group, and each with30 cases. The control group was given routine treatment of Western medicine, while the observation group received Xiongbi decoction based on the control group. The treatment process was 8 weeks respectively. To compare the clinical effect, TCM syndrome score, angina pectoris frequency and time, ECG and cardiac function of the two groups before and after treatment. Results：The TCM syndrome score of the two groups was significantly lower than before the treatment （P 〈 0.05） ; the difference between the two groups before and after the treatment was statistically significant （P 〈 0. 05 ） ; the difference between the two groups was statistically significant （ P 〈 0.05 ） ; the two groups of patients had electrocardiogram and cardiac function. After treatment, the index was significantly better than before treatment, and the difference was statistically sig- nificant （P 〈 0.05）. The frequency and time of angina pectoris in the two groups were significantly lower than that before treatment, and the difference was statistically significant （P 〈 0.05 ）. The difference between the two groups of cardiac function indexes, the frequency and time of angina pectoris, and the difference between the two groups before and after the treatment was statistically significant （P 〈 0.05）. Conclusion： Xiongbi Decoction in the treatment of coronary heart disease unstable angina pectoris has significant effect and is worthy of clinical reference.