腹腔镜下肝癌切除术治疗原发性肝癌的临床效果观察

Clinical Efficacy of Laparoscopic Resection of Hepatocellular Carcinoma for Primary Liver Cancer

目的:探讨腹腔镜下肝癌切除术治疗原发性肝癌的临床效过。方法:选取我院住院部2013年5月-2018年4月间收治的58例原发性肝癌患者,根据手术方法将其分为对照组(n=24)和观察组(n=34),对照组采用常规开腹肝癌切除术治疗,观察组采用腹腔镜下肝癌切除术治疗。比较两组患者术后1周肝功能变化及临床并发症发生情况。结果:两组患者术前TBIL、AST及ALT水平比较,差异均无统计学意义(P>0.05);术后1周,两组TBIL、AST及ALT均显著下降(P<0.05),观察组TBIL、AST及ALT水平均显著低于对照组(P<0.05);观察组术后并发症发生率为8.82%(3/34),明显低于对照组的29.17%(7/24),差异有统计学意义(P<0.05)。结论:腹腔镜下肝癌切除术治疗原发性肝癌的效果显著,患者术后肝功能恢复快,并发症发生率低,是一种安全有效的治疗手段,可进行临床推广应用。

Objective：To investigate the clinical efficacy of laparoscopic hepatectomy for primary livercancer.Method：A total of 58 patients with primary liver cancer admitted to our hospital from May 2013 to April2018 were selected.According to different surgical methods,the patients were divided into control group（n=24）and observation group（n=34）.The control group was treated with routine open hepatectomy,and the observationgroup was treated with laparoscopic combined hepatectomy.The changes of liver function and clinical complicationswere compared between two groups at 1 week after operation.Result：There were no significant differences in thelevels of TBIL,AST and ALT between two groups before operation（P〉0.05）.TBIL,AST and ALT in two groupsdecreased significantly 1 week after operation（P〈0.05）.The levels of TBIL,AST and ALT in the observationgroup were significantly lower than those in the control group（P〈0.05）.The total incidence of postoperativecomplications in the observation group was 8.82%,was significantly lower than 29.17% in the control group（P〈0.05）.Conclusion：Laparoscopic hepatectomy is a safe and effective method for the treatment of primaryhepatocellular carcinoma.It can be widely used in clinic.