左炔诺孕酮宫内节育系统治疗子宫腺肌病的效果观察

Effect of Levonorgestrel Intrauterine System in Treatment of Adenomyosis

目的:分析左炔诺孕酮宫内节育系统治疗子宫腺肌病的效果。方法:选取2016年3月-2017年2月本院收治的100例子宫腺肌病患者,按照随机数字表法将其分为观察组和对照组,各50例。对照组采用孕三烯酮药物治疗,观察组采用左炔诺孕酮宫内节育系统治疗。观察两组治疗效果、不良反应及治疗前后月经量、痛经分值、子宫体积、子宫内膜厚度。结果:观察组总有效率为94.00%,明显高于对照组的78.00%(P<0.05);治疗后,观察组月经量、子宫内膜厚度、子宫体积及痛经分值均低于对照组,比较差异均有统计学意义(P<0.05);观察组不良反应发生率为2.00%,明显低于对照组的16.00%(P<0.05)。结论:子宫腺肌病患者采用左炔诺孕酮宫内节育系统治疗的效果较为理想,能有效改善患者临床症状,恢复正常的临床指标,且安全性较高。

Objective：To analyze the effect of Levonorgestrel Intrauterine System in treatment of adenomyosis.Method：A total of 100 patients with adenomyosis treated in our hospital from March 2016 to February 2017 were selected,according to the random number table method,they were divided into observation group and control group,50 cases in each group.The control group was treated with Gestrinone,while observation group was treated with Levonorgestrel Intrauterine System.The therapeutic effects,adverse reactions,and menstrual volume,dysmenorrhea score,uterine volume and endometrial thickness before and after treatment of two groups were observed.Result：The total effective rate of observation group was 94.00%,which was significantly higher than 78.00% of control group（P〈0.05）.After treatment,the menstrual volume,endometrial thickness,uterine volume and dysmenorrhea score of observation group were lower than those of control group,the differences were statistically significant（P〈0.05）.The incidence of adverse reactions in observation group was 2.00%,which was significantly lower than 16.00% in control group（P〈0.05）.Conclusion：The effect of Levonorgestrel Intrauterine System in treatment of adenomyosis is ideal,can effectively improve the clinical symptoms of patients and restore the normal clinical indicators,and the safety is high.