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脑白质疏松症患者血清同型半胱氨酸与认知功能的关系及其意义 被引量:3

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摘要 目的 :探讨血清同型半胱氨酸(homocysteine, Hcy)与脑白质疏松症(leukoaraiosis, LA)及认知水平的关系。方法:根据头颅磁共振成像结果,将108例脑梗死患者分为脑梗死合并LA组和单纯脑梗死组,采用酶循环速率法测定血清Hcy水平。同时测试LA患者的认知损害程度。结果:脑梗死合并LA组Hcy浓度为(18.8±4.4)μmol/L,单纯脑梗死组为(13.8±3.5)μmol/L,两组比较差异具有统计学意义(P<0.001)。血清Hcy水平随LA患者认知障碍程度的加重而升高(P<0.05)。结论:Hcy与LA关系密切,Hcy水平越高,认知损害越重。
出处 《南通大学学报(医学版)》 2018年第5期350-352,共3页 Journal of Nantong University(Medical sciences)
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