北京市丰台区部分社区卒中高危人群血脂情况及其危险因素研究

Analysis of Dyslipidemia and Its Risk Factors in Community Population with High-risk of Stroke at Fengtai District of Beijing

目的梳理北京市丰台区40岁以上卒中高危人群血脂情况及主要危险因素。方法纳入5401例卒中高危人群病例,依据血脂四项结果分为血脂异常人群(4174例)及血脂正常人群(1209例),收集一般资料、卒中高危因素、生活习惯及家族病史信息,通过单因素分析筛选体质指数(bodymassindex,BMI)、糖尿病、吸烟、高血压、明显超重或肥胖、口味偏油、不饮或很少饮奶制品纳入多因素Logistic回归分析血脂异常的危险因素。结果血脂异常检出率为77.54%,知晓率为67.23%,用药率为23.50%,其中血脂异常与糖尿病、吸烟相关(P<0.05),与BMI、高血压、明显超重或肥胖、不饮或很少饮奶制品显著相关(P<0.01),糖尿病[比值比(odds ratio,OR)1.187,95%可信区间(confidence interval,Cl)1.025～1.374]、BMI(OR 1.097,95%Cl 1.076～1.118)及不饮或很少饮奶制品(OR 1.147,95%Cl 1.006～1.308)为血脂异常的独立危险因素(P<0.05)。结论梳理北京市丰台区卒中高危人群血脂情况,发现血脂异常率高,知晓率低,糖尿病、BMI、奶制品摄入不足均为其高危因素。

Objective To investigate dyslipidemia and its related risk factors in community population aged 〉40 years old and with high-risk of stroke at Fengtai district of Beijing. Methods A total of 5401 subjects were included in this study. According to the level of blood lipid, all the subjects were divided into dyslipidemia group （n=4174） and normal plasma lipid group （n=1209）. After a single factor analysis of possible risk factors, body mass index （BMI）, diabetes, smoking, hypertension, obesity, tasting greasy food, lack of dairy were screened and included in multifactor Logistic regression analysis to analyze the risk factors of dyslipidemia. Results The prevalence, awareness and drug taking rate of dyslipidemia were 77.54%, 67.23% and 23.50%, respectively. Diabetes and smoking were correlated with dyslipidemia （P〈0.05）, and BMI, hypertension, obesity, lack of dairy were strongly associated with dyslipidemia （P〈0.01）. Diabetes [odds ratio （OR） 1.187, 95% confidence interval （CI） 1.025-1.374], BMI （OR 1.097, 95%CI 1.076-1.118） and lack of dairy （OR 1.147, 95%CI 1.006-1.308） were independent risk factors of dyslipidernia （P〈0.05）.Conclusions The prevalence of dyslipidemia in community population with high risk of stroke was high, and diabetes, BMI, lack of dairy and low awareness rate were independent risk factors of dyslipidemia.