2015—2017年辽宁省肿瘤医院麻醉药品使用情况分析

Analysis on usage of narcotic drugs in Liaoning Cancer Hospital and Institute from 2015 to 2017

目的分析2015—2017年辽宁省肿瘤医院麻醉药品的应用情况及变化趋势,为临床合理用药提供参考。方法通过医院数据系统收集2015—2017年麻醉药品数据,对麻醉药品的消耗量、销售金额、用药频度(DDDs)、限定日费用(DDC)及药品排序比(B/A)等进行统计分析。结果 2015—2017年麻醉药品的销售总金额持续增长,盐酸羟考酮缓释片(40、10 mg)的销售金额增长远高于总金额增长速度,芬太尼透皮贴剂(8.4、4.2 mg)的销售量持续下降。羟考酮缓释片有替代芬太尼透皮贴剂的趋势。各麻醉药品DDC值2015年与2016年完全相同,2017年各麻醉药品DDC值均有所下降。B/A值接近1.00的麻醉药品有盐酸吗啡注射液、盐酸吗啡控释片、盐酸吗啡片(10mg)、盐酸哌替啶注射液和阿片片。结论 2015—2017年辽宁省肿瘤医院麻醉药品在临床上的应用基本合理。

Objective To investigate the usage and variation tendency of narcotic drugs in Liaoning Cancer Hospital and Institute from 2015 to 2017, in order to provide reference for rational use of drugs in clinic. Methods The usage of narcotic drugs in Liaoning Cancer Hospital and Institute from 2015 to 2017 were collected, and the consumption quantity, consumption sum, defined daily dose system（DDDs）, defined daily cost（DDC）, and drug sequence ratio（B/A） were calculated and compared. Results The total consumption sum of narcotic drugs showed a steady increase from 2015 to 2017, among which Oxycodone Hydrochloride Prolonged-release Tablets（40 and 10 mg） showed a highest increase compared to others. On the other hand, consumption sum of Fentanyl Transdermal Patches（8.4 and 4.2 mg） was decreased every year. There was a tendency that Fentanyl Transdermal Patches were being replaced by Oxycodone Hydrochloride Prolonged-release Tablets. DDC of all the narcotic drugs in 2015 was exactly the same as that in 2016, and was decreased in 2017. B/A of Morphine Hydrochloride Injection, Morphine Hydrochloride Controlled-release Tablets, Morphine Hydrochloride Tablets（10 mg）, Pethidine Hydrochloride Injection, and Opium tablets（50 mg） were close to 1.00. Conclusion The utilization of narcotic drugs in Liaoning Cancer Hospital and Institute is basically rational.