2015—2017年湖北省肿瘤医院麻醉性镇痛药的使用情况分析

Analysis on utilization of anesthetic analgesic drugs in Hubei Cancer Hospital from 2015 to 2017

目的分析2015—2017年湖北省肿瘤医院麻醉性镇痛药的使用情况,为临床合理使用提供依据。方法调取湖北省肿瘤医院2015—2017年麻醉性镇痛药的相关用药信息,对使用金额、用药频度(DDDs)及药品排序比(B/A)进行统计与分析。结果 2015—2017年,麻醉性镇痛药物的销售金额逐年增加;销售金额前3位的分别为注射用盐酸瑞芬太尼、盐酸氢吗啡酮注射液、硫酸吗啡缓释片。麻醉性镇痛药物的DDDs排序基本稳定,DDDs前3位的分别为盐酸羟考酮缓释片、硫酸吗啡缓释片和盐酸氢吗啡酮注射液。2015年磷酸可待因片、盐酸哌替啶注射液、盐酸吗啡片(10、30mg)的B/A为1.00。结论 2015—2017年湖北省肿瘤医院麻醉性镇痛药的使用基本合理,在无创给药方面仍需要进一步提升。

Objective To analyze the utilization of anesthetic analgesic drugs in Hubei Cancer Hospital from 2015 to 2017, and so as to provide reference for rational use of drugs. Methods The utilization information of anesthetic analgesic drugs in Hubei Cancer Hospital from 2015 to 2017 was extracted, and the consumption sum, defined daily doses（DDDs）, and drug sequence ratio（B/A） were analyzed statistically. Results From 2015 to 2017, the total consumption sums of anesthetic analgesic drugs were increased year by year. Consumption sums of Remifentanil Hydrochloride for injection, Hydromorphone Hydrochloride Injection, and Morphine Sulfate Sustained Release Tablets were ranked in the top 3. DDDs of anesthetic analgesic drugs were relatively stable. DDDs of Oxycodone Hydrochloride Prolonged-release Tablets, Morphine Sulfate Sustained Release Tablets, and Hydromorphone Hydrochloride Injection were ranked in the top 3. B/A of Codeine Phosphate Tablets, Pethidine Hydrochloride Injection, and Morphine Hydrochloride Tablets（10, 30 mg） were close to 1.00 in 2015. Conclusion The use of anesthetic analgesic drugs in Hubei Cancer Hospital from 2015 to 2017 is reasonable on the whole, but there is still a need to continue to promotion in noninvasive drug delivery.