中医综合疗法治疗强直性脊柱炎临床观察

Clinical Observation of Comprehensive Therapy of Chinese Medicine for Ankylosing Spondylitis

目的:观察中医综合疗法治疗强直性脊柱炎的临床疗效。方法:选取190例强直性脊柱炎患者作为研究对象,随机分成2组各95例,对照组以常规西药治疗,观察组采用独活寄生汤内服联合中药熏蒸、埋针、肢体功能锻炼等综合治疗方法。2组均治疗3月。观察2组治疗前后的巴斯强直性脊柱炎疾病活动性指数(BASDAI)、患者疾病总体评价(PGA)评分,统计疗效与安全性情况。结果:观察组总有效率94.74%,对照组总有效率76.84%,2组比较,差异有统计学意义(P <0.05)。治疗后,2组BASDAI评分和PGA评分均较治疗前下降(P <0.05);观察组PGA评分低于对照组(P <0.05),但2组BASDAI评分无统计学差异(P> 0.05)。2组安全性情况无统计学差异(P> 0.05)。结论:中医综合治疗可有效缓解强直性脊柱炎患者的病情,提高患者的生活质量,且具有较好的安全性。

Objective： To observe the clinical effect of comprehensive therapy of Chinese medicine for ankylosing spondylitis. Methods： Selected 190 cases of patients with ankylosing spondylitis as study subjects and divided them into two groups randomly, 95 cases in each group. The control group was given routine western medicine, while the observation group was given the oral administration of Duhuo Jisheng tang combined with the comprehensive therapies of treatment such as Chinese herbal fumigation and washing, needle-embedding therapy and limb function exercises. The treatment for both groups lasted for 3 months. Observed the scores of Bass ankylosing spondylitis disease activity index （BASDAI） and patient global assessment （PGA） before and after treatment and recorded the curative effect and safety. Results： The total effective rate was 94.74% in the observation group and 76.84% in the control group, difference being significant （P 〈 0.05）. After treatment, the scores of BASDAI and PGA in the two groups were decreased when compared with those before treatment （P 〈 0.05）. The PGA score in the observation group was lower than that in the control group （P 〈 0.05）, but there was no significant difference being found in the comparison of BASDAI scores between the two groups （P 〉 0.05）. There was no significant difference being found in the comparison of safety between the two groups （P 〉 0.05）. Conclusion： The application of comprehensive therapy of Chinese medicine, better safety, can effectively alleviate the condition of patients with ankylosing spondylitis and improve the quality of life of patients.