癃闭舒胶囊联合中药穴位贴敷治疗良性前列腺增生症临床研究

Clinical Observation of Longbishu Capsules Combined with Acupoint Application of Chinese Medicine for Benign Prostatic Hyperplasia

目的:观察癃闭舒胶囊联合中药穴位贴敷治疗良性前列腺增生症的临床疗效。方法:选取60例良性前列腺增生症患者作为研究对象,随机分为对照组和观察组各30例。对照组给予坦索罗辛缓释片联合非那雄胺片治疗,观察组在对照组基础上加用癃闭舒胶囊联合中药穴位贴敷治疗,2组疗程均为1月。对比分析2组临床疗效,观察治疗前后患者的前列腺体积(PV)、最大尿流率(Qmax)及残余尿量(PVR)的变化,记录不良反应情况。结果:观察组治疗总有效率93.33%,对照组治疗总有效率70.00%,2组比较,差异有统计学意义(P <0.05)。治疗后,2组PV均较治疗前缩小,Qmax均较治疗前提升,PVR均较治疗前减少,差异均有统计学意义(P <0.05);观察组PV小于对照组,Qmax大于对照组,PVR少于对照组,差异均有统计学意义(P <0.05)。结论:在常规西药治疗基础上加用癃闭舒胶囊联合中药穴位贴敷治疗良性前列腺增生症临床疗效显著,可明显改善患者的症状,无不良反应,值得临床推广应用。

bjective： To observe the clinical effect of Longbishu capsules combined with acupoint application of Chinese medicine for benign prostatic hyperplasia. Methods： Selected 60 cases of patients with benign prostatic hyperplasia admitted into our hospital as study subjects, and divided them into the control group and the observation group randomly, 30 cases in each group. The control group was given tamsulosin sustained-release tablets combined with finasteride tablets for treatment, while the observation group was additionally given Longbishu capsules combined with acupoint application of Chinese medicine. The treatment for both groups lasted for one month. Compared and analyzed the clinical effect in the two groups, observed the changes of prostate volume（PV）, maximum urinary flow rate（Qmax） and volume of post-void residual （PVR） of patients before and after treatment, and recorded the adverse reactions. Results： After treatment, the total effective rate was 93.33% in the observation group and 70.00% in the control group, the difference being significant（P 〈 0.05）. After treatment, PV in the two groups was decreased when compared with that before treatment respectively; Qmax were improved when compared with those before treatment and PVR was decreased when compared with that before treatment, differences being significant （P 〈 0.05）. PV in the observation group was less than that in the control group; Qmax was higher than that in the control group and PVR was less than that in the control group, differences being significant （P 〈 0.05）. Conclusion： Based on the treatment of the routine western medicine, the therapy of Longbishu capsules combined with acupoint application of Chinese medicine has significant clinical effect in treating benign prostatic hyperplasia, which can effectively improve the symptoms of patients without adverse reaction and it is worthy of promotion and application in clinical practice.