固冲摄血汤辅助治疗脾肾阳虚型围绝经期功能失调性子宫出血临床观察

Clinical Observation of Guchong Shexue Tang in Adjuvant Treatment of Dysfunctional Uterine Bleeding in Perimenopause with Yang Deficiency of Spleen and Kidney Type

目的:观察固冲摄血汤辅助治疗脾肾阳虚型围绝经期功能失调性子宫出血的临床疗效,及对患者血红蛋白(Hb)的影响。方法:选取13 0例脾肾阳虚型围绝经期功能失调性子宫出血患者,随机分为观察组和对照组各65例。2组均采用诊刮术进行基础治疗,对照组术后予米非司酮片治疗,观察组予固冲摄血汤治疗。对比分析2组临床疗效,观察治疗前后Hb含量的变化,记录复发情况。结果:观察组总有效率9 2.3%,对照组总有效率81.5%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组Hb水平均较治疗前上升,差异均有统计学意义(P<0.01);观察组Hb水平高于对照组,差异有统计学意义(P<0.01)。观察组复发率13.3%(8/60),对照组复发率3 7.7%(20/53),2组比较,差异有统计学意义(P<0.05)。结论:固冲摄血汤辅助治疗脾肾阳虚型围绝经期功能失调性子宫出血临床疗效确切,可提高患者的Hb含量,减少复发。

Objective：To observe the clinical effect of Guchong Shexue tang in adjuvant treatment of dysfunctional uterine bleeding in perimenopause with yang deficiency of spleen and kidney type and its effect on hemoglobin（Hb） of patients. Methods：Selected 130 cases of patients with dysfunctional uterine bleeding in perimenopause of yang deficiency of spleen and kidney type and divided them into the observation group and the control group randomly, 65 cases in each group. The two groups received curettage for basic treatment. The control group was treated with mifepristone tablets after operation,while the observation group was treated with Guchong Shexue tang. Compared and analyzed the clinical effect in the two groups,observed the changes of the content of Hb before and after treatment, and recorded the recurrence. Results： The total effective rate was 92.3% in the observation group and was 81.5% in the control group,the difference being significant（P〈0.05）. After treatment,Hb levels in the two groups were increased when compared with those before treatment,differences being significant（P〈0.01）. Hb level in the observation group was higher than that in the control group,the difference being significant（P〈0.01）. The recurrence rate was 13.3%（8/60） in the observation group and was 37.7%（20/53）in the control group,the difference being significant（P〈0.05）. Conclusion：The therapy of Guchong Shexue tang in adjuvant treatment of dysfunctional uterine bleeding in perimenopause with yang deficiency of spleen and kidney type has accurate clinical effect, which can improve the content of Hb of patients and reduce the recurrence.