疏风解毒汤联合西药治疗急性分泌性中耳炎临床研究

Clinical Observation of Shufeng Jiedu Tang Combined with Western Medicine for Acute Secretory Otitis Media

目的:观察疏风解毒汤联合西药治疗急性分泌性中耳炎的临床疗效。方法:选取82例急性分泌性中耳炎患者作为研究对象,随机分为对照组与实验组各4 1例。对照组给予西药治疗,实验组在对照组用药基础上联合疏风解毒汤内服。治疗前后对2组患者声导抗测听鼓室图、气导阈值、中医证候评分进行对比分析,并评价治疗效果。结果:治疗后,2组气导阈值及中医证候评分均较治疗前下降(P<0.01);实验组气导阈值及中医证候评分均低于对照组(P<0.01)。治疗前所有患者鼓室声阻抗检查均为B型或C型。治疗后,实验组3 8例恢复A型,3例未恢复;对照组3 1例恢复A型,10例未恢复。实验组鼓室声阻抗检查结果优于对照组(P<0.05)。实验组治疗总有效率9 2.6 8%,高于对照组的75.6 1%,差异有统计学意义(P<0.05)。实验组不良反应发生率14.6 3%,对照组不良反应发生率19.51%,2组比较,差异无统计学意义(P>0.05)。治疗后随访3月,2组均未见复发。结论:疏风解毒汤联合西药治疗急性分泌性中耳炎,能够显著提升患者听力,提高治疗效果,且不良反应较小。

Objective：To observe the clinical effect of Shufeng Jiedu tang combined with western medicine for acute secretory otitis media. Methods：Selected 82 cases of patients with acute secretory otitis media as research objects,and divided them into the control group and the experiment group randomly,41 cases in each group. The control group was given western medicine for treatment,while the experiment group additionally received the oral administration of Shufeng Jiedu tang. Before and after treatment, compared and analyzed tympanogram via acoustic immittance measurement, air-conduction thresholds and Chinese medicine syndrome scores of patients in both groups, and evaluated the clinical effect. Results： After treatment, air-conduction thresholds and Chinese medicine syndrome scores in both groups were lower than those before treatment（P〈0.01）, air-conduction thresholds and Chinese medicine syndrome scores in the experiment group were respectively lower than those in the control group（P〈0.01）. Before treatment, the results of acoustic impedance inspection of all the patients were type B or type C. After treatment, 38 cases in the experiment group reverted to type A, and 3 cases did not revert; 31 cases in the control group reverted to type A, and 10 cases did not revert. The results of acoustic impedance inspection in the experiment group were better than those in the control group（P〈0.05）. The total effective rate was 92.68% in the experiment group and 75.61% in the control group, difference being significant（P〈0.05）. The incidence of adverse reactions was 14.63% in the experiment group and 19.51% in the control group,difference being insignificant（P〉0.05）. During3 months of follow-up after treatment,there was no case of recurrence in both groups. Conclusion：Shufeng Jiedu tang combined with western medicine treating acute secretory otitis media can significantly improve the hearing of patients and promote the clinical effect with no adverse reactions.