摘要
AIM: To study whether female-specifc prostheses are superior to conventional prostheses after total knee arthroplasty (TKA) by conducting this meta-analysis to evaluate the effects of the 2 different designs.METHODS: A systematic electronic search was con-ducted in the databases of PubMed, EMBASE and the Cochrane Library for prospective and retrospective trials. Meta-analysis was performed for the outcomes, includ-ing range of motion (ROM), Knee Society score, Hospi-tal for Special Surgery scores (HSS) and complications including deep infection, manipulation under anesthesia (MUA), revisions, anterior knee pain, deep vein throm-bosis and overhang rate. Meta-analysis was conductedwhere applicable. Weighted mean difference (WMD) and odds ratio were calculated according to study type.RESULTS: Seven studies including 1174 knees wereeligible for data extraction and pooled analysis. The overhang rate of female-specifc prostheses was signif-cantly lower than the conventional ones (WMD, 3.25; 95%CI: 0.00-0.27; P = 0.001). ROM in the female-spe-cifc prostheses group after TKA tended to be greater than the conventional prostheses group; however, with insignifcant difference (WMD, 2.48; 95%CI: -0.83-5.78; P = 0.14). HSS (WMD, 0.48; 95%CI: -1.45-0.88; P = 0.63) and complications including deep infection (WMD, 0.39; 95%CI: 0.19-3.08; P =0 .70), MUA (WMD, 1.53; 95%CI: 0.02-1.61; P = 0.13) and revisions (WMD, 0.55; 95%CI: 0.07-4.34; P = 0.13) were all comparable be-tween the two groups with at least 1 year follow-up. Other indexes were revealed to be similar between the two treatments with a descriptive analytical method.CONCLUSION: Although the overhang rate is lower with female-specific prostheses, the current evidence does not support that female-specific prostheses out-weigh conventional ones after TKA.
AIM: To study whether female-specific prostheses are superior to conventional prostheses after total knee arthroplasty(TKA) by conducting this meta-analysis to evaluate the effects of the 2 different designs.METHODS: A systematic electronic search was conducted in the databases of Pub Med,EMBASE and the Cochrane Library for prospective and retrospective trials.Meta-analysis was performed for the outcomes,including range of motion(ROM),Knee Society score,Hospital for Special Surgery scores(HSS) and complications including deep infection,manipulation under anesthesia(MUA),revisions,anterior knee pain,deep vein thrombosis and overhang rate.Meta-analysis was conducted where applicable.Weighted mean difference(WMD) and odds ratio were calculated according to study type.RESULTS: Seven studies including 1174 knees wereeligible for data extraction and pooled analysis.The overhang rate of female-specific prostheses was significantly lower than the conventional ones(WMD,3.25; 95%CI: 0.00-0.27; P = 0.001).ROM in the female-specific prostheses group after TKA tended to be greater than the conventional prostheses group; however,with insignificant difference(WMD,2.48; 95%CI:-0.83-5.78; P = 0.14).HSS(WMD,0.48; 95%CI:-1.45-0.88; P = 0.63) and complications including deep infection(WMD,0.39; 95%CI: 0.19-3.08; P =0.70),MUA(WMD,1.53; 95%CI: 0.02-1.61; P = 0.13) and revisions(WMD,0.55; 95%CI: 0.07-4.34; P = 0.13) were all comparable between the two groups with at least 1 year follow-up.Other indexes were revealed to be similar between the two treatments with a descriptive analytical method.CONCLUSION: Although the overhang rate is lower with female-specific prostheses,the current evidence does not support that female-specific prostheses outweigh conventional ones after TKA.