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普萘洛尔联合安体舒通治疗肝硬化门静脉高压所致胃食管静脉曲张破裂出血的效果观察

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摘要 目的 :研究用普萘洛尔联合安体舒通治疗肝硬化门静脉高压所致胃食管静脉曲张破裂出血的效果。方法 :将某医院接诊的100例肝硬化门静脉高压所致胃食管静脉曲张破裂出血患者随机分为观察组与对照组。为对照组患者单用普萘洛尔进行治疗,为观察组患者联用普萘洛尔和安体舒通进行治疗。然后比较两组患者肝静脉压力梯度(HVPG)的改善情况和再次出血的发生率。结果:治疗后,两组患者的HVPG均较治疗前显著下降,P <0.05;观察组患者的HVPG低于对照组患者,P <0.05。在治疗后12个月、18个月及24个月,观察组患者再次出血的发生率均低于对照组患者,P <0.05。结论 :用普萘洛尔联合安体舒通治疗肝硬化门静脉高压所致胃食管静脉曲张破裂出血可显著降低患者的HVPG和再次出血的发生率。
作者 王丹
出处 《当代医药论丛》 2018年第19期89-90,共2页
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