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Immunological aspects of drug-induced liver injury

Immunological aspects of drug-induced liver injury
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摘要 Drug induced liver injury(DILI) is a common condition of increasing incidence. Many environmental and genetic factors are involved in its pathogenesis,and immunological mechanisms are also thought to contribute to the development and severity of DILI. This review summarizes current understanding of the immunological pathogenesis of DILI and discusses the perspective for clinical applications. Drug induced liver injury (DILI) is a common condition of increasing incidence. Many environmental and ge-netic factors are involved in its pathogenesis, and im-munological mechanisms are also thought to contribute to the development and severity of DILI. This review summarizes current understanding of the immunologi-cal pathogenesis of DILI and discusses the perspective for clinical applications.
出处 《World Journal of Immunology》 2014年第3期149-157,共9页 世界免疫学杂志
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