中医补气活血法在冠心病无症状心肌缺血患者中的治疗观察

Treatment of Silent Myocardial Ischemia in Patients with Coronary Heart Disease by TCM Invigorating Qi and Activating Blood Circulation

目的探讨中医补气活血法在冠心病无症状心肌缺血患者中的治疗效果。方法选取我院(2015年1月至2017年1月)收治的冠心病无症状心肌缺血患者86例为研究对象,均经临床检查确诊,根据不同治疗方法将本研究对象分为两组,对照组(n=43)给予常规西医治疗,观察组(n=43)在对照组基础上给予中医补气活血法治疗,对比两组患者临床疗效和治疗前后ST段压低变化情况、心肌耗氧量指数、收缩压水平、心率以及不良反应发生情况。结果两组患者临床疗效对比差异明显,具有统计学意义(P<0.05)。治疗前两组患者ST段压低总次数和ST段压低持续时间对此差异不明显,无统计学意义(P>0.05);治疗后两组患者ST段压低总次数和ST段压低持续时间均明显下降,但观察组患者下降更为明显,具有统计学意义(P<0.05)。治疗前两组患者心肌耗氧量指数和收缩压水平以及心率对比差异不明显,无统计学意义(P>0.05);治疗后两组患者心肌耗氧量指数和收缩压水平以及心率均明显下降,但观察组患者下降更为明显,具有统计学意义(P<0.05)。两组患者不良反应发生率18.60%/16.28%对比差异不明显,无统计学意义(P>0.05)。结论中医补气活血法治疗冠心病无症状心肌缺血效果显著,值得临床推广。

Objective To explore the therapeutic effect of TCM invigorating qi and activating blood circulation in patients with coronary heart disease withsilent myocardial ischemia. Methods 86 cases of coronary heart disease with asymptomatic myocardial ischemia in our hospital （January 2015-January 2017）were selected as the subjects, all of them were diagnosed by clinical examination. According to different treatment methods, the subjects were divided into twogroups, the control group （n=43） was given conventional western medicine, and the observation group （n=43） was given to the control group on the basis of thecontrol group. The clinical efficacy of two groups of patients was compared with the changes of ST segment depression, myocardial oxygen consumption index,systolic blood pressure level, heart rate and adverse reaction. Results There was a significant difference in the clinical efficacy between the two groups （P 〈0.05）.The total number of ST segment depression and the duration of ST segment depression in the two groups were not significant, and there was no statisticalsignificance （P 〉0.05）. The total frequency of ST segment depression and the duration of ST segment depression in the two groups were significantly decreased,but the decrease in the observation group was more obvious, and was statistically significant （P 〈0.05）. There was no significant difference in myocardial oxygenconsumption index, systolic pressure level and heart rate contrast between the two groups before treatment （P 〉0.05）. After treatment, the myocardial oxygenconsumption index and systolic blood pressure level and heart rate decreased significantly in the two groups, but the decrease in the observation group was moreobvious, with statistical significance （P 〈0.05）. There was no significant difference in the incidence of adverse reactions between the two groups （18.60%/16.28%）.There was no significant difference between the two groups （P 〉0.05）. Conclusion Chinese medicine invigorating qi and activating blood therapy is effective intreating asymptomatic myocardial ischemia of coronary heart disease, and is worthy of clinical promotion.[