自发性脑出血致脑死亡器官捐献供体脏器功能维护71例总结

Maintenance of 71 brain dead organ donation donors caused by spontaneous cerebral hemorrhage

目的探讨自发性脑出血致脑死亡器官捐献供体在脏器维护方面的特点及处理对策.方法回顾性分析本院2015年3月至2018年6月期间完成的自发性脑出血致脑死亡供体共71例的临床资料,总结这些供体的特点及处理方法.结果71例供体最终67例完成器官捐献,4例因出现脓毒血症无法捐献;5例肌酐值持续较高,肾穿刺病理提示不可逆病变未获取肾脏;1例因转氨酶持续升高未获取肝脏.共产出大器官194个,其中肾脏124例,肝脏66例,心脏4例.结论自发性脑出血致脑死亡供体有其自身特点,通过积极供体脏器维护,可获得较好结局.

Objective To explore the characteristics and organ maintenance method of brain dead organ donation donors caused by spontaneous cerebral hemorrhage. Methods The clinical data of 71 brain dead organ donation donors caused by spontaneous cerebral hemorrhage in our hospital from March 2015 to June 2018 was retrospectively analyzed, then summarized the characteristics and treatment methods of the donors. Results 67 donors completed organ donation from the 71 cases, 4 cases were unable to donate due to sepsis. The kidney of 5 cases were discarded because of high creatinine value and irreversible lesions suggested by renal biopsy; the liver of 1 case was not acquired due to the continuous increase of transaminase. There were 194 donor organs, including 124 kidneys, 66 livers, 4 hearts. Conclusion The brain dead organ donation donors caused by spontaneous cerebral hemorrhage have their own characteristics, a better outcome can be achieved through active maintenance of the donor organ.