2013-2014年新疆维吾尔自治区成年居民血脂异常流行状况及其相关因素

Analysis on epidemiological characteristics and related factors of dyslipidemia among adultresidents of Xinjiang Uygur Autonomous Region during 2013-2014

目的探讨新疆维吾尔自治区（新疆）不同民族常住成年居民血脂异常流行状况及相关因素。方法2013--2014年在新疆8个监测县（市、区）采用多阶段分层整群随机抽样，调查了4120名18岁及以上的汉族和维吾尔族常住居民。采用问卷调查和身体测量的方法收集血脂异常相关因素的信息，酶法检测总胆固醇、甘油三酯、HDL．C和LDL．C的含量。采用χ2检验比较血脂异常、高胆固醇血症、高甘油三酯血症、低HDL-C血症和高LDL-C血症检出率在不同人群之间的差异。采用多因素非条件logistic回归模型分析血脂异常的相关因素。结果新疆成年常住居民血脂异常检出率为45．00％（1854例），维吾尔族居民血脂异常检出率[47．80％（977／2044）1高于汉族[42．24％（877／2076）]（χ2=12．84，P〈0．001）。维吾尔族居民中，相对于男性、居住在农村、BMI〈24．0kg／m2、非中心型肥胖、非糖尿病人群，女性、居住在城市、超重、肥胖、中心型肥胖、患有糖尿病人群的血脂异常发生风险0R（95％CI）值分另0为0．41（0．33-0．51）、0．54（0．39-0．76）、1．52（1．18-1．96）、2．20（1．64-2．96）、1．66（1．29-2．14）、1．49（1．06-2．11）；汉族居民中，相对于BMI〈24．0kg／m2、非中心型肥胖、不吸烟、非糖尿病、非高血压人群，超重、肥胖、中心型肥胖、吸烟、患有糖尿病、非高血压人群的血脂异常发生风险0R（95％CI）值分另U为1．72（1．32-2．25）、2．60（1．85-3．64）、1．45（1．13-1．87）、1．46（1．09-1．95）、1．77（1．38-2．25）、1．62（1．31-2．00）。结论新疆常住成年居民的血脂异常检出率高于全国水平，维吾尔族居民血脂异常检出率高于汉族。维吾尔族居民中，性别、城乡、BMI、中心型肥胖、糖尿病与血脂异常有关；汉族居民中，BMI、中心型肥胖、吸烟、糖尿病和高血压与血脂异常有关。

Objective To study the epidemiological characteristics and related factors of dyslipidemia among adult residents in Xinjiang Uygur Autonomous Region （Xinjiang） in 2013-2014. Methods A total of 4 120 adult residents consisting of Han and Uygur group aged over 18 years old were selected by using a stratified cluster random sampling method in 8 counties of Xinjiang from 2013 to 2014. The related factors of dyslipidemia were collected by questionnaire and physical measurement. The total cholesterol, trlglyceride, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol were detected by enzyme method. Factors associated with dyslipidemia were analyzed by chi-squared test and a multivariate unconditioned logistic regression model adjusted for gender, urban or rural area, age-group, body mass index （BMI）, central obesity, smoking, drinking, education attainment, diabetes mellitus and hypertension. Results The prevalence of dyslipidemia was 45.00% （1 854 cases）. The prevalence of dyslipidemia was higher in Uygur group （47.80% （977/2 044）） than that in Han group （42.24% （877/2 076）） （χ2=12.84, P〈0.001）. The analysis showed that dyslipidemia was related with gender （OR=0.41, 95%C1： 0.33-0.51）, urban area （OR=0.54, 95%CI： 0.39-0.76）, BMI （overweight group （OR=1.52, 95%CI： 1.18-1.96）; obesity group （OR=2.20, 95%C1： 1.64-2.96））, central obesity （OR=1.66, 95%CI： 1.29-2.14） and diabetes mellitus （OR=1.49, 95%CI： 1.06-2.11） in Uygur group. The analysis also showed that dyslipidemia was related with BMI （overweight group （OR=1.72, 95%CI： 1.32-2.25）, obesity group （OR=2.60, 95%CI： 1.85-3.64））, central obesity （OR=1.45, 95%CI： 1.13-1.87）, smoking （OR=1.46, 95%CI： 1.09-1.95）, diabetes mellitus （OR=1.77, 95%CI： 1.38-2.25） and hypertension （OR=1.62, 95%CI： 1.31-2.00） in Han group. Conclusions The prevalence of dyslipidemia in Xinjiang was higher than the national average prevalence. The prevalence of dyslipidemia in Uygur group was significantly higher than that in Han group. The gender, living area, BMI, central obesity and diabetes mellitus were risk factors of dyslipidemia in Uygur group, and BMI, central obesity, smoking, diabetes mellitus and hypertension were risk factors of dyslipidemia in Han group in Xinjiang.