骨关节炎患者全膝关节置换前骨质疏松相关因素的分析

The Analysis of Osteoporosis Related Factors in Patients with Osteoarthritis before Total Knee Replacement

为探讨骨关节炎患者全膝关节置换前骨质疏松情况及其相关因素，本研究选取2014年3月至2016年6月本院收治的90例膝骨关节炎患者进行骨密度测定。根据骨密度结果将患者分为骨质疏松组和非骨质疏松组，记录两组患者的年龄、性别、BMI、伴发疾病及t值和z值，并分析骨密度与观察指标的相关性。研究显示，在全膝关节置换前的膝骨关节炎患者中，女性患者的骨质疏松发生率显著高于男性患者（p〈0.05）；年龄和肥胖是髋骨密度独立的危险因素，髋骨密度与BMI呈正相关关系、与年龄呈负相关关系。因此，对于年龄≥65岁、BMI〈25kg／m^2的患者，尤其是女性患者，全膝关节置换前要进行必要的骨密度检测，以掌握其骨质疏松程度。

To investigate the osteoporosis and related factors in patients with osteoarthritis before total knee arthroplasty, A total of 90 patients with knee osteoarthritis admitted to our hospital from March 2014 to June 2016 were selected for bone mineral density determination. According to the bone mineral density results, the patients were divided into osteoporosis group and non-osteoporosis group. The age, gender, BMI, associated disease, t and Z values of the two groups were recorded, and the correlation between bone mineral density and observation index was analyzed. Studies had shown that in patients with knee osteoarthritis before total knee arthroplasty, the incidence ofosteoporosis in women is significantly higher than in male patients （p〈0.05）; age and obesity were indep- endent risk factors for hip bone density, hip bone density was positively correlated with BMI and negatively correlated with age. Therefore, for patients whose age ≥ 65 and BMI 〈25 kg/m^2, especially female patients, the nebone density should be tested for the degree of osteoporosis before total knee arthroplasty.