雷珠单抗联合577nm激光对视网膜静脉阻塞合并黄斑水肿患者视力及视网膜厚度的影响

Effect of Ranibizumab combined with 577nm laser on visual acuity and retinal thickness in patients with retinal vein occlusion complicated with macular edema

目的分析视网膜静脉阻塞合并黄斑水肿患者应用雷珠单抗联合577nm激光治疗后效果。方法采用随机数字表法将我院105例视网膜静脉阻塞合并黄斑水肿患者分组,对照组52例给予577nm激光治疗,观察组53例联合雷珠单抗治疗,对比两组患者治疗后视网膜厚度及视力变化。结果观察组治疗后视力提升率60.38%高于对照组38.46%,视力降低率9.43%低于对照组32.70%,治疗后CMT、BCAV均低于对照组(P<0.05)。结论雷珠单抗联合577nm激光能够有效降低视网膜静脉阻塞合并黄斑水肿患者黄斑区视网膜厚度,改善视力。

Objective To analyze the effect of Ra~,：blzumab combined with 577nm laser in the treatment of retinal vein occlusion complicated with macular edema. Methods 105 cases of retinal vein occlusion with macular edema were divided into two groups. 52 cases in the control group were treated with 577nm laser, and 53 cases in the observation group were treated with Ranibizumab. The retinal thickness and visual acuity after treatment were compared between the two groups. Results The visual acuity improvement rate of the observation group was 60.38%, which was higher than that of the control group （38.46%）. The visual acuity rate was 9.43% in the observation group, which was lower than that of the control group （32.70%）. After treatment, CMT and BCAV in the observation group were lower than those of the control group （P〈0.05）. Conclusions Ranibizumab monoclonal antibody combined with 577nm laser can effectively reduce macular retinal thickness and improve vision in patients with retinal vein occlusion and macular edema.