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硝普钠联合多巴胺治疗急性心力衰竭的临床观察 被引量:4

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摘要 目的探讨硝普钠联合多巴胺在急性心力衰竭(AHF)中的治疗价值。方法随机选取急性心力衰竭患者58例,按随机数表法分为对照组与观察组,每组29例。两组均予以常规治疗,对照组加用硝普钠,观察组采用硝普钠联合多巴胺治疗,比较两组治疗效果,记录胱抑素C与尿微量水平变化情况,观察肾功能(24 h尿量、血尿素氮、血肌酐、血清钾)改善效果。结果观察组(93. 10%)有效率高于对照组(72. 41%),差异有统计学意义(P <0. 05);观察组治疗后7 d、14 d的胱抑素C(CysC)、β2微球蛋白(β2-MG)、α1微球蛋白(α1-MG)、血肌酐(Scr)、血尿素氮(BUN)低于对照组,24 h尿量高于对照组,差异有统计学意义(P <0. 05);观察组不良反应发生率(3. 45%)与对照组(6. 90%)比较差异未见统计学意义(P> 0. 05)。结论 AHF患者采用硝普钠与多巴胺联合治疗,能提高临床疗效,并且可通过调节尿微量蛋白与CysC水平,改善肾功能。
出处 《临床医学》 CAS 2018年第10期97-99,共3页 Clinical Medicine
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