小儿支原体肺炎体液免疫功能与hs-CRP检验的临床价值体会

Experience of humoral immunity and hs-CRP test in children with mycoplasma pneumonia

目的:探讨小儿支原体肺炎体液免疫功能与hs-CRP(超敏C反应蛋白)检验的临床价值体会。方法:选择2016年9月-2018年3月我院儿科收治的90例MPP患儿作为观察对象,依据病情严重程度分为A组(n=46,重症组)和B组(n=44,轻症组),另选取45例健康儿童作为对照组,所有受试者均进行体液免疫功能与hs-CRP检验,比较三组检测结果的差异。结果:A组、B组患儿血浆IgM、IgG、hs-CRP、水平均明显高于对照组,IgA明显低于对照组,组间存在统计学差异(P <0.05);A、B组间比较,A组IgM、IgG、hs-CRP、水平高于B组,IgA低于对照组,组间具有统计学意义(P <0.05)。结论:体液免疫功能与hs-CRP检验对准确诊断小儿支原体肺炎和深入了解病情发展情况具有重要价值,可为临床制定治疗方案和判断预后提供参考和借鉴,具有积极推广和普及意义。

Abstract Objective： To explore the experience of humoral immunity and hs-crp test in children with mycoplasma pneumonia. Methods： 90 cases of children with MPP admitted to and treated in our hospital from September 2016 to March 2018 were selected as research subjects, and divided into group A （n = 46, the severe group） and group B （n = 44, the mild group） according to the illness severity,another 45 cases of healthy children were selected as the control group, all the subjects received the humoral immune function and the hs-CRP test, the diference of the three groups of test results was compared Results： Plasma IgM, IgG, hs-crp level of children in group A and group B were signifcantly higher than those in the control group, and IgA was signifcantly lower than that in the control group, there were statistically signifcant diferences between the groups （P 〈 0.05）. Comparison between group A and group B showed that IgM, IgG, hs-crp levels in group A were higher than those in group B and IgA was lower than that in the control group, which was with statistical signifcance （P 〈 0.05）. Conclusion： Humoral immunity and hs-crp test were of great value for accurate diagnosis of pediatric mycoplasma pneumonia and in-depth understanding of the development of the disease. They could provide references for clinical treatment plans and prognosis judgment, and were of positive promotion and popularization signifcance.