大气颗粒物污染与血糖关系的系统综述

A systematic review on association betw een particulate matter and blood glucose

已有研究发现大气颗粒物污染与糖尿病的患病率存在统计学联系。为更好地了解这一关系,对探讨颗粒物污染(PM_(10)/PM_(2.5))与血糖水平相关性的研究展开系统综述。在中国知网、万方、Pub Med、Web of Science检索1997年1月至2017年12月国内外关于颗粒物污染与血糖水平关系的研究,同时对参考文献也进行了追溯。共纳入15项研究,多数显示颗粒物污染与血糖水平的升高存在统计学意义,在不同地区、不同人群中,具体的效应值有所不同。老年人群、女性人群和超重人群是可能的易感人群。目前关于颗粒物污染与血糖水平关系的研究数量仍较少,未来仍需大量研究基于个体水平的暴露数据,更精确地探索不同人群中颗粒物污染与血糖之间的关系。

Studies have indicated that there was a statistical association between particulate matter and the prevalence of diabetes. In order to have a better understanding on this relationship,we summarized the current evidence about the relationship between particulate matter（ PM10/PM2.5） and blood glucose level. Studies on the relationship between particulate matter（ PM10/PM2.5） and blood glucose level were searched through the databases of National Knowledge Infrastructure,Wanfang,Pub Med and Web of Science published from January 1997 to December 2017,and the references in the included studies were also traced. A total of 15 studies were included in the review. Most studies showed that the association between particulate matter and elevated blood glucose levels were statistically significant,with specific effect values varying in different regions and populations. The elderly,female and overweight population may be susceptible populations. The current number of studies on the relationship between particulate matter and blood glucose is still limited. In the future,more accurate studies based on personal exposure will be needed to explore the relationship between particulate matter and blood glucose in different populations.