雷尼替丁与奥美拉唑治疗消化系统溃疡的效果对比

Effect comparison of Ranitidine and Omeprazole in the treatment of peptic ulcer

目的分析并对比雷尼替丁与奥美拉唑治疗消化系统溃疡的效果。方法选取2017年6月~2018年6月我院收治的90例消化系统溃疡患者作为研究对象,依据随机数字表法将其分为对照组(45例)与观察组(45例)。对照组患者给予雷尼替丁治疗,观察组患者给予奥美拉唑治疗。观察并比较两组患者的治疗总有效率及不良反应发生情况。结果观察组患者的总有效率(97.78%)高于对照组(84.44%),差异有统计学意义(P<0.05)。观察组患者的不良反应总发生率为17.78%,低于对照组的37.78%,差异有统计学意义(P<0.05)。结论与雷尼替丁相比,奥美拉唑治疗消化系统溃疡的效果更显著。

Objective To analyze and compare the effect of Ranitidine and Omeprazole in the treatment of peptic ulcer.Methods A total of 90 patients with peptic ulcer from June 2017 to June 2018 in our hospital were selected as the research objects. According to the random number table method, they were divided into the control group（45 cases） and the observation group（45 cases）. The control group was treated with Ranitidine, and the observation group was treated with Omeprazole. The total effective rate and adverse reactions were observed and compared between the two groups.Results The total effective rate of the observation group was 97.78%, which was higher than that of the control group（84.44%）, with significant difference（P〈0.05）. The total incidence of adverse reactions in the observation group was17.78%, which was significantly lower than that in the control group accounting for 37.78%, with significant difference（P〈0.05）. Conclusion Omeprazole is more effective than Ranitidine in the treatment of peptic ulcer.