加味二妙散配合别嘌醇治疗痛风性肾病的临床研究

Clinical Research of Gouty Nephropathy Treated with Combination of Ermiaosan Addition Decoction and Allopurinol

目的观察加味二妙散配合别嘌醇治疗痛风性肾病的临床疗效。方法 80例痛风性肾病患者按随机数字表法分为两组,对照组采用西医常规治疗,治疗组在对照组的基础上加用加味二妙散治疗;分别观察两组的临床疗效。结果治疗组总有效率为72.50%,高于对照组的50.00%(P <0.05),治疗组治疗后血尿酸水平低于对照组(P <0.05),胱抑素水平相近(P> 0.05)。结论应用中西医结合方法治疗痛风性肾病的疗效优于单用西医治疗。

Objective： To observe the clinical efficacy of Ermiaosan Addition Decoction combined with allopurinol in the treatment of gouty nephropathy. Methods： 80 patients were randomly divided into treatment group and control group. The control group was treated with routine western medicine. The treatment group was treated with Ermiaosan Addition Decoction on the basis of the control group. Results： The total effective rate of treatment group was 72.50%,which was higher than that of control group（50.00%）（P〈0.05）. The level of serum uric acid in the treatment group was lower than that in the control group（P〈0.05）,and the cystatin level was similar（P〈0.05）. Conclusion： The application of integrated traditional Chinese and Western medicine for gouty nephropathy is better than western medicine alone.