中国社区控烟干预效果评价的Meta分析

Effectiveness of community-based smoking intervention programs in China: a meta-analysis

目的评价我国社区控烟干预的效果,为开展社区控烟干预提供依据。方法检索中国生物医学文献数据库、中国知网、万方数据知识服务平台、维普中文科技期刊数据库、 PubMed、 Embase、 Scopus、 Cochrane对照试验中心注册库(CENTRAL)、护理和保健文献积累索引(CINAHL)及教育资源信息中心(ERIC),收集从建库至2018年3月22日中国社区控烟干预的文献,以相对危险度(RR)和95%置信区间(95%CI)为干预效果测量指标,采用R 3.3.3软件进行分析。结果共检索到相关文献1 699篇(中文文献978篇,英文文献721篇),最终纳入文献23篇(中文文献22篇,英文文献1篇),其中以吸烟率为指标的研究16篇,合并效应RR=0.77 (95%CI:0.70~0.85);以戒烟率为指标的研究7篇,合并效应RR=3.47 (95%CI:2.08~5.81)。Egger's检验和漏斗图均显示没有发表偏倚(P>0.05)。敏感性分析显示结果较为稳定。结论我国社区控烟干预能够有效预防人群吸烟并促进吸烟者戒烟。

Objective To evaluate the effectiveness of community smoking intervention programs in China and to provide evidence for further programs. Methods Relevant articles published before March 22,2018 were identified by searching China Biology Medicine disc,China National Knowledge Infrastructure,Wanfang Database,VIP,PubMed,Embase,Scopus,CENTRAL,CINAHL and ERIC. Intervention effects were calculated as relative risk（RR）and 95% confidence interval（95%CI）. The meta-analysis was performed by R 3.3.3 software. Results A total of 1 699 related articles（978 articles in Chinese and 721 articles in English）were retrieved,of which 23 studies（22 articles in Chinese and 1 article in English）were included in the analysis. Sixteen articles reported the smoking rate and their pooled RR was 0.77（95%CI：0.70-0.85）;seven articles reported the smoking cessation rate and their pooled RR was 3.47（95%CI：2.08-5.81）. Funnel plots and Egger＇s weighted regression showed no publication bias（P〉0.05）. Sensitivity analysis showed that the results were relatively stable. Conclusion Community smoking intervention can effectively prevent smoking and promote smoking cessation.