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湖州市艾滋病患者抗病毒治疗服药依从性分析 被引量:12

Adherence to highly active antiroviral therapy among patients with HIV or AIDS in Huzhou
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摘要 目的了解湖州市接受高效联合抗反转录病毒治疗(HAART)艾滋病患者的服药依从性及影响因素,为提高艾滋病患者HAART治疗效果提供依据。方法从中国艾滋病综合防治信息系统收集湖州市674例接受HAART治疗的艾滋病患者资料,通过随访面对面调查服药依从性情况,采用Logistic回归模型分析艾滋病患者服药依从性的影响因素。结果共调查674例接受HAART治疗的艾滋病患者,其中男性584例,占85.65%;女性90例,占13.35%。年龄为20~82岁,平均(42.64±13.59)岁。近1个月漏服药物≤2次的有644例,服药依从性比例为95.55%。Logistic回归分析结果显示,艾滋病患者抗病毒治疗后发生不良反应(OR=2.279, 95%CI:1.088~4.773),病毒载量≥400copies/mL (OR=2.630, 95%CI:1.373~5.038)是服药依从性的影响因素。结论湖州市接受HAART治疗的艾滋病患者服药依从性比例较高,发生药物不良反应和病毒载量≥400 copies/mL是患者服药依从性的影响因素。
出处 《预防医学》 2018年第12期1231-1233,共3页 CHINA PREVENTIVE MEDICINE JOURNAL
基金 湖州市科技计划项目(2017GY26)
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