分娩监护镇痛系统在足月初产妇中的应用效果

The effect of SRL998 delivery monitoring analgesia system or epidural anesthesia on primiparas with full term vaginal delivery

目的:比较SRL998分娩监护镇痛系统和硬膜外麻醉在足月初产妇中的应用。方法:收集2017年1月-2018年4月本院收治的足月初产妇276例,随机分为观察组(138例)和对照组(138例),观察组给予SRL998分娩监护镇痛系统镇痛治疗,对照组给予硬膜外麻醉镇痛治疗,观察两组孕产妇镇痛效果、应激反应、产程时间、孕产妇及新生儿临床结局。结果:疼痛视觉模拟评分镇痛后两组均较镇痛前降低(P<0.05),但镇痛前和镇痛后10min组间比较均无差异(P>0.05)。C反应蛋白、皮质醇两组产前无差异(P>0.05),产后24h观察组比对照组降低(P<0.05)。观察组第一产程时间、第二产程时间均比对照组缩短(P<0.05)。两组孕产妇和新生儿并发症无统计学差异(P>0.05)。结论:SRL998分娩监护镇痛系统在足月初产妇中可以达到较好的镇痛效果,具有无创性,可降低孕产妇应激反应和产程时间。

Objective To compare the application of SRL998 delivery monitoring analgesia system and epidural anesthesia on primiparas with full term vaginal delivery. Methods： 276 primipara who were treated in Hongdong county medical group people＇s hospital from January 2017 to April 2018 were divided into observation group （n=138） and control group （n=138）. The primiparas in observation group were given the SRL998 delivery monitoring analgesic system for analgesic treatment, the primiparas in control group were given epidural anesthesia for analgesic treatment. The analgesic effect, stress response, duration of labor, clinical outcomes of primiparas, and neonatal clinical outcomes were compared between the two groups. Results： After analgesia, the visual analogue scale scores of primiparas in the two groups were significant lower than those of primiparas before analgesia （ P 〈0.05）. There was no significant different in the visual analogue scale scores of primiparas before analgesia and 10min after analgesia between the two groups （ P 〉0.05）. There were no significant difference in the levels of C reactive protein and cortisol of primiparas before labore between the two groups （ P 〉0.05）, but the levels of C reactive protein and cortisol of primiparas in observation group were significant lower than those of primiparas in control group at 24h after delivery （ P 〈0.05）. When compared with the control group, the duration of the first stage of labor and the second stage of labor of primiparas in observation group were significantly shortened （ P 〈0.05）. The rate of maternal and neonatal complications of primiparas in the two groups had no statistically significant different （ P 〉0.05）. Conclusion： The SRL998 delivery monitoring system can achieve better analgesic effect for primiparas, and it has no invasive, can reduce the stress response, and can short labor time.