右美托咪定麻醉前滴鼻在小儿临床麻醉中的效果分析

Analysis of the Effect of Dexmetomidine before Anaesthesia on Clinical Anesthesia in Children

目的探讨右美托咪定麻醉前滴鼻在小儿临床麻醉中的应用效果。方法选取2017年3月~2018年2月本院收治86例手术患儿,根据入院时间分为对照组和观察组各43例。对照组采用咪达唑仑麻醉前滴鼻,观察组采用右美托咪定麻醉前滴鼻,对比两组不同时间点生命体征、镇静效果、疼痛程度、术后躁动发生率及术后呼吸道不良事件发生率。结果两组RR、HR、SpO_2水平在不同时间点对比,差异无统计学意义(P>0.05);观察组Ramsay评分较对照组高,CHEOPS评分较对照组低,差异有统计学意义(P<0.05);观察组术后躁动发生率及术后呼吸道不良事件总发生率均较对照组低,差异有统计学意义(P<0.05)。结论小儿临床麻醉中采用右美托咪定麻醉前滴鼻可有效维持患儿生命体征稳定,提升镇静及镇痛效果,降低术后躁动及呼吸道不良事件发生率。

Objective To investigate the clinical effect of dexmetomidine nasal drops before anesthesia in children. Methods From March 2017 to February 2018, 86 children with surgical treatment were selected and divided into two groups, 43 eases in each group. The control group was treated with midazolam before anesthesia and the observation group with dexmetomidine before anesthesia. The vital signs, sedation effect, pain degree, postoperative restlessness rate and incidence of postoperative adverse events of respiratory tract were compared between the two groups at different time points. Results＇ There was no significant difference between the two groups in the level of RR、HR、SpO2 at different time points （P〉0.05）.The Ramsay score of the observation group was lower than that of the control group （P〈0.05）, and the incidence of postoperative restlessness and respiratory adverse events in the observa tion group was lower than that in the control group（P〈0.05）.Conclusion The use of dexmetomidine before anesthesia can effectively maintain the stability- of vital signs, improve the sedative and analgesic effect, and reduce the incidence of postoperative restlessness and adverse respiratory events in children with clinical anesthesia.