百忧解对急性脑梗死预后的影响

Effect of Fluoxetine on the Prognosis of Acute Cerebral Infraction

目的探究百忧解对急性脑梗死患者的预后效果,并对其具体疗效进行分析。方法将该院自2016年1月—2017年12月收治的90例急性脑梗死患者作为本次研究的对象,采用随机分组的方法平均分为观察组和对照组,其中对照组采用常规治疗方法而观察组则在常规治疗的基础上使用百忧解进行治疗,4周后,采用抑郁自评量表(SDS)、日常生活能力(ADL)评分标准进行测评,并对患者的治疗满意度进行统计,由此从总体上对两组的治疗效果进行对比。结果两组患者在治疗前SDS和ADL评分比较差异无统计学意义(P>0.05)。治疗4周后,两组SDS和ADL评分与治疗前比较均降低,且观察组降低更加明显,与对照组比较,差异有统计学意义(P<0.05);观察组的治疗满意度为95.56%,对照组治疗满意度为46.67%,表示组间数据差异有统计学意义(χ~2=5.493,P=0.02)。结论在对急性脑梗死患者进行预后治疗时在常规治疗的基础上使用百忧解能够有效的提高患者的治疗效果,改善患者的抑郁情况和ADL能力,具有重要的研究意义。

Objective To study the fluoxetine on the prognosis of acute cerebral infraction and analyze the specific curative effect. Methods 90 eases of patients with acute cerebral infraction admitted and treated in our hospital from January 2016 to December 2017 were selected and randomly divided into two groups, the control group used the routine therapy, while the observation group were treated with fluoxetine on the basis of the routine therapy, and the patients were evaluated by the SDS and ADL scale after four weeks, and the satisfactory degree of treatment of patients was counted, and the treatment effect was compared between the two groups. Results There were no significant differences in SDS and ADL scores between the two groups before treatment （P〉0.05）. After 4 weeks of treatment, the SDS and ADL scores of the two groups were lower than those before treatment, and the decrease was more obvious in the obser- vation group. Compared with the control group, The difference was statistically significant（P〈0.05）; and the treatment satisfactolT degree in the observation group and in the control group was respectively 95.56% and 46.67%（χ^2=5.493,P= 0.02）, and the difference was obvious, with statistical significance. Conclusion The fluoxetine in patients with acute cerebral infi＇aetion on the basis of the routine therapy can effectively improve the treatment effect and improve the de- pression condition and ADL ability, and it is of important research significance.