综合护理干预对非小细胞肺癌化疗患者胃肠道反应及生活质量的影响

Effect of comprehensive nursing interventions on chemotherapy-induced gastrointestinal reactions and quality of life in patients with non-small cell lung cancer

目的探讨综合护理干预对非小细胞肺癌化疗患者胃肠道反应及生活质量的影响。方法选取2017年1月—12月于徐州医科大学附属医院肿瘤内科住院接受治疗的非小细胞肺癌患者80例,按照随机数字表法将患者分为对照组和观察组,各40例。对照组常规护理,观察组在对照组基础上实施综合护理干预方案。观察2组化疗后胃肠道反应和生活质量。结果观察组不良反应发生率低于对照组患者(P <0. 05)。观察组胃肠道反应程度较对照组轻(P <0. 05)。干预后,观察组肺癌患者生存质量测定量表(FACT-L)评分优于对照组(P <0. 05)。结论综合护理干预能够减轻非小细胞肺癌化疗患者的胃肠道反应,提高其生活质量。

Objective To explore the effect of comprehensive nursing interventions on chemotherapy-induced gastrointestinal reactions and quality of life in patients with non-small cell lung cancer （NSCLC）. Methods Totally 80 NSCLC patients with chemotherapy were divided into the observation group and the control group, with 40 cases in each group. Patients in both two groups received routine care during treatment, and those in the observation group adopted a series of comprehensive nursing interventions. The incidence of chemotherapy-induced gastrointestinal reactions and quality of life were assessed and compared between two groups. Results The incidence of chemotherapy-induced gastrointestinal reactions was lower in the observation group than that in the control group（ P 〈0.05）, and patients in the observation group had a less severity of chemotherapy-induced gastrointestinal reactions （ P 〈0.05） . The score of Functional Assessment of Cancer Therapy-Lung （FACT-L） was higher in the observation grouop than that in the control group （ P 〈0.05）. Conclusion Comprehensive nursing interventions are effective to relieve the chemotherapy-induced gastrointestinal reaction and improve the quality of life in NSCLC patients.