子宫内膜异位症患者血清、组织及腹腔液PGE_2、IL-6及OPN表达的变化观察

Observation on the Change of Serum,Tissue and Peritoneal Fluid PGE2,IL-6 and OPN of Patients with Endometriosis

目的观察子宫内膜异位症患者血清、组织及腹腔液PGE2、IL-6及OPN表达的变化。方法选取2016年6月至2018年5月的130例子宫内膜异位症患者为观察组,同期的130例子宫肌瘤患者为对照组。比较两组的子宫内膜异位症患者血清、组织及腹腔液PGE2、IL-6及OPN表达,比较观察组不同分期者的检测结果。结果观察组的血清、组织及腹腔液PGE2、IL-6及OPN高于对照组(P <0.05),观察组中分期较高者的检测结果高于分期较低者(P <0.05)。结论子宫内膜异位症患者血清、组织及腹腔液PGE2、IL-6及OPN均呈现高表达,且分期较高者的表达也较高。

Objective To observe the change of serum,tissue and peritoneal fluid PGE2, IL-6 and OPN of patients with endometriosis. Methods 130 patients withendometriosis from June 2016 to May 2018 were as the observation group, 130 patients with hysteromyoma at the same time were as the control group.Then theserum, tissue and peritoneal fluid PGE2, IL-6 and OPN of two groups were compared, and the detection results of observation group with different stages werecompared. Results The serum, tissue and peritoneal fluid PGE2, IL-6 and OPN of observation group were higher than those of control group（P 〈0.05）, the detectionresults of observation group with higher stages were higher than those of patients with lower stages（P 〈0.05）. Conclusion The serum, tissue and peritoneal fluid PGE2,IL-6 and OPN of patients with endometriosis show higher expression, and the expression of patients with higher stages are higher too.