右美托咪定对颅内动脉瘤介入治疗患者血流动力学影响的探究

Study on the effect of dexmedetomidine on hemodynamics in patients with intracranial aneurysm intervention

目的探讨右美托咪定对颅内动脉瘤介入治疗患者血流动力学的影响。方法选取本院2017年3月至2018年3月期间收治的颅内动脉瘤患者60例为研究对象,给予患者实施介入治疗,随机分为2组,对照组为常规麻醉,观察组应用右美托咪定麻醉,对比2组麻醉情况。结果进入手术室前,2组的MAP、SBP、HR、DBP比较差异无统计学意义(P>0.05);插管后、诱导前、自主呼吸恢复时,观察组的MAP、SBP、HR、DBP低于对照组,差异有统计学意义(P<0.05)。结论右美托咪定对颅内动脉瘤介入治疗患者血流动力学的影响较小,血流动力学较稳定,有利于介入治疗的实施,值得应用。

Objective To investigate the effect of dexmedetomidine on hemodynamics of patients with intracranial aneurysm intervention. Selection methods in our hospital during March 2017 to March 2017 were 60 patients with intracranial aneurysm as the research object, give, interventional therapy for the randomly divided into 2 groups, control group for general anesthesia, observation group application right beautiful mi on anesthesia, compared two groups of anesthesia. Results before entering the operating room, there was no statistically significant difference in MAP, SBP, HR and DBP between the two groups（P〉0.05）. MAP, SBP, HR and DBP of the observation group were lower than those of the control group after intubation, before induction and during the recovery of spontaneous respiration（P〈0.05）. Conclusion dexmedetomidine has less effect on hemodynamics in patients with intracranial aneurysm interventional therapy.