摘要
Multiple sclerosis(MS)is a chronic disorder affecting central nervous system(CNS)in which inflammatory and neuro-degenerative features coexist since the earlier phases of the disease(Reich et al.,2018).During last years,attention has been directed toward the possible pathogenic pathways linking these two different features characterizing MS,in order to acquire a better understanding of the disease pathogenesis and to design new disease modifying therapies.Currently available therapies for MS are primarily
Multiple sclerosis （MS） is a chronic disorder affecting central ner- vous system （CNS） in which inflammatory and neuro-degenerative features coexist since the earlier phases of the disease （Reich et al., 2018）. During last years, attention has been directed toward the possible pathogenic pathways linking these two different features characterizing MS, in order to acquire a better understanding of the disease pathogenesis and to design new disease modifying therapies.
基金
MDF received support by Fondazione Italiana Sclerosi Multipla(FISM)(project code 2013/R/12)
LGa received travel grants from Biogen-Idec,Biogen,Novartis,Teva,Genzyme
MDF participated on advisory boards for and received speaker or writing honoraria and funding for travelling from Bayer,Biogen Idec,Genzyme,Merck,Novartis,Roche and Teva
