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Interstitial Cajal-like cells arrhythmogenic potential substrate of pulmonary veins

Interstitial Cajal-like cells arrhythmogenic potential substrate of pulmonary veins
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摘要 Interstitial Cajal-like cells(ICLC) have been found in the atrium,ventricle and pulmonary vein in human and anmials.ICLC with very long processes and space structure,Cell processes establish close spatial relationships between each other, as well as with cardiomyocyte and nerve endings.ICLC appear located among the myocardial cells and particularly at the border between the myocardial sleeve and pulmonary vein wall.ICLC seems to possess automaticity and triggered activity.ICLC is a potential substrate for arrhythmia. Interstitial Cajal-like cells(ICLC) have been found in the atrium,ventricle and pulmonary vein in human and anmials.ICLC with very long processes and space structure,Cell processes establish close spatial relationships between each other, as well as with cardiomyocyte and nerve endings.ICLC appear located among the myocardial cells and particularly at the border between the myocardial sleeve and pulmonary vein wall.ICLC seems to possess automaticity and triggered activity.ICLC is a potential substrate for arrhythmia.
作者 卢少平
出处 《South China Journal of Cardiology》 CAS 2010年第2期129-136,共8页 岭南心血管病杂志(英文版)
关键词 Interstitial Cajal-like cells ARRHYTHMIA Interstitial Cajal-like cells arrhythmia
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参考文献3

  • 1Hirohiko Iwasaki,Masayoshi Kajimura,Satoshi Osawa,Shigeru Kanaoka,Takahisa Furuta,Mutsuhiro Ikuma,Akira Hishida. A deficiency of gastric interstitial cells of Cajal accompanied by decreased expression of neuronal nitric oxide synthase and substance P in patients with type 2 diabetes mellitus[J] 2006,Journal of Gastroenterology(11):1076~1087
  • 2Yi-Jen Chen,Shih-Ann Chen,Yao-Chang Chen,Hungh-I Yeh,Mau-Song Chang,Cheng-I Lin. Electrophysiology of single cardiomyocytes isolated from rabbit pulmonary veins: implication in initiation of focal atrial fibrillation[J] 2002,Basic Research in Cardiology(1):26~34
  • 3Jüri J. Rumessen,Alban de Kerchove d’Exaerde,Séverine Mignon,Florence Bernex,Jean-Pierre Timmermans,Serge N. Schiffmann,Jean-Jacques Panthier,Jean-Marie Vanderwinden. Interstitial cells of Cajal in the striated musculature of the mouse esophagus[J] 2001,Cell and Tissue Research(1):1~14

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