光相干断层扫描成像技术的进化

Evolution of optical coherence tomography

光相干断层扫描成像(optical coherence tomography,OCT)是一种无创、快速的光学医学诊断成像模式,已成为生物医学领域的研究热点。近年来,许多功能性OCT技术不断涌现,包括多普勒OCT、偏振敏感OCT、光谱OCT、光相干断层扫描弹性成像等。这些新技术为观察、理解组织活动提供了当前其他成像技术所无法实现的新方法,从而拓宽了OCT技术在临床的应用前景。

Optical coherence tomography （OCT） is a non-invasive, rapid optical medical imaging modality and has become a hot topic in biomedical research. In recent years, several functional OCTs have emerged, including Doppler OCT, polarization-sensitive OCT, spectroscopic OCT, and optical coherence tomographic elastography, etc. These newer advances in functional OCT broaden the potential clinical application of OCT by providing novel ways to observe and understand tissue activity that cannot be accomplished by other current imaging methodologies.