肺力咳合剂与氨溴特罗口服液对小儿急性支气管炎的效果对照研究

A controlled study on treating acute bronchitis with Feilike mixture and ambroxol and clenbuterol oral solution

目的:研究肺力咳合剂与氨溴特罗口服液在治疗小儿急性支气管炎中的效果差异。方法:选择2016年7月-2017年12月我院儿科收治的急性支气管炎患儿中抽取出85例,随机分成两组,A组患儿给予氨溴特罗口服液,B组患儿给予肺力咳合剂,对比治疗总有效率等。结果:B组患儿的治疗总有效率为100.0%明显高于A组的88.37%,P <0.05;且B组的退热时间、咳嗽消失时间、肺啰音消失时间均明显短于A组,P <0.05;两组患儿治疗期间均未出现明显不良反应;B组患儿治疗5d后喘息、咳嗽、咳痰症状评分较A组明显降低(P <0.05);B组患儿治疗5d后PEF、FEV1较A组明显升高(P <0.05)。结论:与氨溴特罗口服液相比,肺力咳合剂在小儿急性支气管炎治疗中更有优势,利于促进患儿临床症状的缓解,缩短治疗疗程,值得推广。

Objective： To observe the effect of Feilike mixture （ 肺力咳合剂 ） and ambroxol and clenbuterol oral solution on acute bronchitis. Methods： 85 children with acute bronchitis were randomly divided into group A and group B. Group A was treated with ambroxol and clenbuterol oral solution; group B was treated with Feilike mixture. Results： The total effective rate was 100% in group B, higher than 88.37% in group A （P〈0.05）. The antipyretic time, cough disappeared time and pulmonary rales disappeared time in group B was shorter than group A （P〈0.05）. There was no significant adverse effects in two groups. After 5d treatment, wheezing, coughing, coughing up phlegm symptom score in group B was lower than groupA （P〈0.05）, PEF, FEV1 in group B was higher than group A （P〈0.05）. Conclusion： Feilike mixture on acute bronchitis is more effective than ambroxol and clenbuterol oral solution, can relieve the clinical symptoms, shorten the treatment course, and worthy of promotion.