摘要
目的:观察普瑞巴林、甲钴胺联合中药汤剂身痛逐瘀汤,用于糖尿病周围神经病变治疗的有效性、可行性。方法:以2015年7月-2016年5月我院收治的64例痛性糖尿病周围神经病变患者为研究对象,并采用双盲法对患者进行随机分组,本次临床将患者分为单一组、中西组,每组32例。单一组用普瑞巴林、甲钴胺,中西组加用身痛逐瘀汤,观察治疗前后患者神经反射情况,对患者治疗效果以及疼痛改善情况进行评估。结果:中西组改善有效率为96.9%,明显高于单一组的87.5%,中西组治疗效果好,同时用药后两组疼痛感均有明显改善,中西组较单一组患者疼痛感减轻效果好,P <0.05。入院时患者神经反射功能测评比较,差异无统计学意义,P> 0.05;用药后中西组神经反射功能恢复明显优于单一组,差异具有统计学意义,P<0.05。结论:临床对痛性糖尿病周围神经病变患者治疗时,以普瑞巴林、甲钴胺联合身痛逐瘀汤治疗,患者神经功能恢复好、疼痛改善好。
Objective: To observe clinical efficacy of the Shentong Zhuyu decoction (身痛逐瘀汤 ) plus pregabalin and mecobalamin on painful diabetic peripheral neuropathy. Methods: From July 2015 to May 2016, 64 cases were divided into two groups, 32 cases in each. The control group was given conventional western medicine, including pregabalin and inecobalamin; and the integrative medicine group was given the Shentong Zhuyu decoction. Results: The efficiency in the integrative medicine group was 96.9%, higher than 87.5% in the control group. After treatment, the pain sensation of both groups were significantly improved, and the effect in the integrative medicine group was better, p〈0.05. The recovery of nerve reflex function in the integrative medicine group was significantly better, P〈0.05. Conclusion: The Shentong Zhuyu decoction plus pregabalin and mecobalamin on painful diabetic peripheral neuropathy show a good effect, can improve clinical symptoms.
出处
《中医临床研究》
2018年第32期40-42,共3页
Clinical Journal Of Chinese Medicine
关键词
疗效
甲钴胺
痛性糖尿病周围神经病变
身痛逐瘀汤
普瑞巴林
Efficacy
Mecobalamin
Painful diabetic peripheral neuropathy
The Shentong Zhuyu decoction
Pregabalin