摘要
血管平滑肌细胞表型改变与动脉粥样硬化、介入后再狭窄等病理改变紧密相关。去分化的血管平滑肌细胞可分化为成骨型、炎症型或成纤维母细胞等表型。现从血管平滑肌细胞表型转化及相关机制进行探讨。
Altered phenotype of vascular smooth muscle cells is closely related to the development of atherosclerosis and restenosis of percutaneous coronary intervention.De-differentiation of vascular smooth muscle cells can be transformed to osteoblast,inflammatory or myofibrolast like cells.This paper explores the changed phenotypes of vascular smooth muscle cell and its related mechanisms.
作者
崔源源
王欣
赵福海
CUI Yuanyuan;WANG Xin;ZHAO Fuhai(Cardiovascular Diseases Center,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China)
出处
《心血管病学进展》
CAS
2018年第6期900-903,共4页
Advances in Cardiovascular Diseases
基金
国家自然科学基金面上项目(81473530
81774139)
中国中医科学院博士研究生创新人才培养基金项目资助(CX201701)
关键词
血管平滑肌细胞
表型
机制
Vascular smooth muscle cell
phenotype
Mechanism
