绝经女性血脂异常在冠心病中的研究进展

Research Progress of Dyslipidemia of Postmenopausal Women with Cardiovascular Disease

女性冠心病有其独特的发病规律,心血管病死亡率的增加与危险因素的变化趋势密切相关。雌激素是心血管系统的保护因子,女性在绝经前体内雌激素的含量维持在一定水平,故较少发生心血管事件;但随着女性年龄的增加,卵巢功能生理性衰退,雌激素分泌逐渐减少,保护作用逐渐减弱,绝经女性体内雌激素水平的下降,引起血脂代谢紊乱,血液黏稠度增加,易导致动脉粥样硬化的发生,绝经后女性血脂异常是罹患心血管系统疾病的重要危险因素。

Female has its unique pathogenesis in coronary heart disease,and the increase in cardiovascular disease mortality is closely related to the trend of undesirable changes in risk factors.Estrogen is the protective factor of cardiovascular system.Estrogen in postmenopausal women is maintained at a certain level,so there is less cardiovascular events.But the function of ovarian is declined with the increase of age in female,the secretion of estrogen decreases gradually and the protective effect is weakened.It arises the disorder of blood lipid metabolism and the increase of blood viscosity,which can easily lead to the occurrence of atherosclerosis.Dyslipidemia in postmenopausal women is an important risk factor for cardiovascular disease.