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绝经后女性骨密度与动脉粥样硬化性心血管疾病关系的研究现状 被引量:1

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摘要 随着人口老龄化加重、城镇化进程的加速及生活方式改变,动脉粥样硬化性心血管疾病(atherosclerosis cardiovascular disease,ASCVD)和骨质疏松症(osteoporosis,OP)已成为两大重要公共卫生问题。中国ASCVD危险因素流行趋势明显,发病人数逐步增长,成为中老年人群的常见病。据调查,我国目前ASCVD现患人数约为2.9亿,ASCVD相关死亡构成占40%以上[1];而女性ASCVD发病比男性晚10年左右,绝经后发病率则明显上升,至65~70岁时发病率与男性相当[2]。
出处 《全科医学临床与教育》 2018年第6期665-667,共3页 Clinical Education of General Practice
基金 浙江省医药卫生科技计划(2018KY495 2019330511)
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  • 1吴宜勇,惠英,邓文慧,周钱,李燕春.盐酸雷洛昔芬防治绝经后骨质疏松症随机双盲对照研究[J].中国新药杂志,2004,13(8):741-744. 被引量:2
  • 2张坚,满青青,王春荣,李红,由悦,翟屹,李莹,赵文华.中国18岁及以上人群血脂水平及分布特征[J].中华预防医学杂志,2005,39(5):302-305. 被引量:112
  • 3Mundy G,Garrett R,Harris S,et al.Stimulation of bone formation in vitro and in rodents by statins.Science,1999,286 (5446):1946-1949.
  • 4Sugiyama M,Kodama T,Konishi K,et al.Compaetin and simvastatins but not pravastatin induce bone morphogenetic protein-2 in humamosteo sarcoma cells.Biochem Biophys ResCommun,2000,271(3):682-692.
  • 5Ohnaka K,Shimoda S,Nawata H,et al.Pitavastatin enhanced BMP-2 and osteocaclin expression by inhibition of Rho2 associated kinase in human osteoblasts.Biochem Biophys Res Commun,2001,287(2):337-342.
  • 6Kuzuya M,Suzuki Y,Asai T,et al.Atorvast atin,3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor,reduces bone resorption in the elderly.J Am Geriatr Soc,2003,51(11):1677-1678.
  • 7Ahn KS,Sethi G,ChaturvediMM,et al.Simvastatin,3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor,suppresses osteoclastogenesis induced by receptor activator of nuclear factor-kap-2 paB ligand through modulation of NF-kap-2 paB pathway.Int J Cancer,2008,123(8):1733-1740.
  • 8Yun-mei Yang,Wei-dong Huang,Qiang-min Xie,Zhe-rong Xu,et al.Simvastatin attenuates TNF-a-induced growth inhibition and apoptosis in murine osteoblastic MC3T3-E1 cells.Inflamm.Res.2010,59:151-157.
  • 9Mendoza S,Noa M,Mas R,et al.Comparison of the effects of D-003,a mixture of high-molecular-weight aliphatic acids from sugarcane wax,and pravastatin on bones and osteoclast apoptosis of ovariectoraized rats.Drugs Exp Clin Res,2005,31 (5-6):181-191.
  • 10王建卫.骨质疏松对大鼠中晚期骨折愈合的影响及辛伐他汀对大鼠骨质疏松性骨折愈合质量的影响(博士论文).

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