摘要
近年来,免疫治疗尤其是免疫检查点抑制剂,在肿瘤治疗中取得了突破性的进展。文章将归纳总结最新的宫颈癌免疫治疗进展,重点阐述免疫检查点抑制剂在宫颈癌中的疗效性、安全性及疗效预测标志物,并对宫颈癌免疫治疗未来的研究方向进行述评。
In recent years,immunotherapy,especially immunological checkpoint inhibitor, has made breakthroughs in cancer therapy.This article will summarize the latest progress in immunotherapy for cervical cancer,focusing on the efficacy,safety and predictive markers of immune checkpoint inhibitors in cervical cancer,and review the future research direction of cervical cancer immunotherapy.
作者
宗丽菊
向阳
ZONG Li-ju;XIANG Yang(Department of Obstetrics and Gynecology,PUMCH Translational Medicine Center,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100730,China)
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2018年第11期1211-1216,共6页
Chinese Journal of Practical Gynecology and Obstetrics
基金
国家自然科学基金(81772783
81472446)
中国医学科学院医学与健康科技创新工程(2017-I2M-1-002)
北京协和医学院研究生创新基金项目(2017-1002-1-13)
关键词
宫颈肿瘤
局部晚期
肿瘤免疫治疗
免疫检查点抑制剂
cervical neoplasm
locally advanced
cancer immunotherapy
immune checkpoint inhibitor