头孢地尼联合奥硝唑治疗盆腔炎的临床效果

Clinical effect of cefdinir combined with ornidazole in the treatment of pelvic inflammatory disease

目的探讨头孢地尼联合奥硝唑治疗盆腔炎的临床效果。方法选择医院2016年1月至2017年3月收治的盆腔炎患者106例,采用信封随机分组方式将其分为常规组和试验组,每组53例。常规组单纯给予奥硝唑治疗,试验组加用头孢地尼治疗,比较两组患者的治疗效果、免疫学指标、血液流变学指标及不良反应发生情况。结果试验组的治疗总有效率显著高于常规组(P<0.05);治疗后,两组的IL-1及CRP水平均显著降低,且试验组均低于常规组,差异具有统计学意义(P<0.05);治疗后,两组的血浆黏度及红细胞压积均显著降低,且试验组均低于常规组(P<0.05);试验组不良反应总发生率显著低于常规组,差异具有统计学意义(P<0.05)。结论盆腔炎患者采用头孢地尼+奥硝唑进行治疗,利于改善临床症状,提高疾病治疗效果,值得临床推广。

Objective To investigate the clinical effect of cefdinir combined with ornidazole in the treatment of pelvicinflammatory disease. Methods A total of 106 patients with pelvic inflammatory disease admitted in the hospital from January2016 to March 2017 were selected and divided into conventional group and experimental group by random grouping ofenvelopes, with 53 cases in each group. The conventional group was treated with ornidazole alone, and the experimentalgroup was treated with cefdinir combined with ornidazole. The treatment effects, immunological parameters, hemorheologicalparameters and adverse reactions of the two groups were compared. Results The total effective rate of treatment in theexperimental group was significantly higher than that of the conventional group （P〈0.05）. After treatment, the levels of IL-1and CRP in the two groups decreased significantly, and those in the experimental group were lower than the conventionalgroup （P〈0.05）. After treatment, the plasma viscosity and hematocrit of the two groups decreased significantly, and those inthe experimental group were lower than the conventional group （P〈0.05）. The total incidence of adverse reactions in theexperimental group was significantly lower than that of the conventional group （P〈0.05）. Conclusion Patients with pelvicinflammatory disease treated with cefdinir ＋ornidazole are beneficial to improve clinical symptoms and increase thetherapeutic effect, which is worthy of clinical promotion.